Background: Age-related cognitive impairment has a negative impact on mental health in the elderly. Ayurveda Rasayana and yoga positively impact cognition and mental health among the elderly. Aims: Present study evaluated the efficacy of Ayurveda Medhya Rasayana (AMR) and Integrated Yoga (IY) on mental health in elderly individuals who had mild cognitive impairment. Materials and Methods: This is a three arms-matched control trial. The study involved 72 elderly subjects who had a mild cognitive impairment (MCI). Of these, 25 received IY, 23 received AMR and, 24 persons received combined (IY plus AMR) intervention for 8 weeks. Stress, anxiety, depression, quality of life, and sleep were assessed by using Perceived Stress Scale, Hamilton Anxiety Rating Scale, Geriatric Depression Scale, Quality of Life in the elderly (CASP-19) and Pittsburg Sleep Quality Index respectively at baseline and after eight weeks. Results: ANOVA shows significant improvement (p<0.05) in quality of life, stress, anxiety, and sleep at eight weeks compared to baseline for all three groups. Depression was significantly improved only in IY plus AMR group. In the between-group comparison, ANCOVA was performed as baseline variable scores were not matched. It shows there was significant difference in groups for stress F (2, 69) = 6.439(p<0.003), anxiety F (2, 69) = 7.581 (p<0.001) and sleep Quality (2, 69) = 4.0449 (p<0.022). Bonferroni post hoc test shows IY plus AMR significantly better than AMR intervention in improving stress, anxiety, and sleep. Conclusion: Combined Ayurveda Medhya Rasayana and Integrated Yoga intervention are better to improve stress, anxiety, and sleep among elderly having mild cognitive impairment than individual treatment. However, further studies are warranted.
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