Angiogenesis is touted as a fundamental procedure in the regeneration and restoration of different tissues. The induction of de novo blood vessels seems to be vital to yield a successful cell transplantation rate loaded on various scaffolds. Scaffolds are natural or artificial substances that are considered as one of the means for delivering, aligning, maintaining cell connection in a favor of angiogenesis. In addition to the potential role of distinct scaffold type on vascularization, the application of some strategies such as genetic manipulation, and conjugation of pro-angiogenic factors could intensify angiogenesis potential. In the current review, we focused on the status of numerous scaffolds applicable in the field of vascular biology. Also, different strategies and priming approaches useful for the induction of pro-angiogenic signaling pathways were highlighted.
Context:Acne vulgaris affects about 85% of teenagers and may continue to adulthood. There are about two million visits to physicians per year for teenagers and the direct cost of acne treatment in the US exceeds $1 billion per year.Evidence Acquisition:A wide variety of treatment regimens exist for acne vulgaris including benzoil peroxide, retinoids, isotretinoids, keratolytic soaps, alpha hydroxy acids, azelaic acid, salicilic acid as well as hormonal, anti-androgen or antiseborrheic treatments. However, none of these methods is free of side effects and their exact role in therapy is not clear. In this paper apart from presenting the possible causes of acne vulgaris and its available drugs, recently published papers about medicinal plants used in the treatment of acne vulgaris were reviewed.Results:Consumption of alternative and complementary medicine, including medicinal plants, is increasing and is common amongst patients affected by acne and infectious skin diseases. Medicinal plants have a long history of use and have been shown to possess low side effects. These plants are a reliable source for preparation of new drugs.Conclusions:Many plants seem to have inhibitory effects on the growth of bacteria, fungi and viruses in vitro. However, there are a few clinical evidences about the effectiveness and safety of these plants in the treatment of acne and other skin infections.
Coronaviruses are a large family of viruses that can cause a variety of diseases in humans. Some coronaviruses cause only mild illnesses like the common cold. While, some coronaviruses such as SARS-CoV (SARS-associated coronavirus) and Middle East respiratory syndrome coronavirus (MERS-CoV) have, in recent years, been able to cause severe respiratory involvement (pneumonia), leading to death in several patients. By identifying the genomic sequence of the new human coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) it has been revealed that it belongs to the beta coronavirus genus. COVID-19 appears to be transmitted by a mechanism similar to the influenza virus via person to person, sneezing coughing, or contact with the secretions of infected patients. Early symptoms of these respiratory viruses include fever, cough, and shortness of breath, with an incubation period of 2-14 days. SARS-CoV-2 is an acute respiratory disease that initially causes lung damage. SARS-CoV-2 can affect other organs, including the kidneys. Kidney damage may be caused by alterations that occur during coronavirus infection. It seems that low-oxygen delivery to tissues like the kidney in the setting of this disease may lead to ischemic damage of the kidney. Considering the importance of the kidneys, as one, this review study aimed to investigate the effect of the new coronavirus on the kidneys and its role in the development of renal failure.
The current article is a descriptive-cross sectional study done to investigate the bacterial contamination in the swimming pools in the fall of 2014, in Shahrekord. 21 samples were taken from low-depth and Abstract Background and Purpose: The swimming pool is an important center of entertainment for the public. Pool area is very suitable for the transmission of various diseases, especially fungal and bacterial contamination. The aim of this study was to identify the fungus Candida Albicans, Aspergillus and Penicillium and different bacterial elements in public swimming pools in the fall of 2014. Methods: In this descriptive study, five public swimming pools were investigated in Shahrekord to examine the water contamination for fungal infection in the swimming pools during autumn of 2014. Sampling was done in two different times, and all the microbiological, chemical, and physical tests were done through standard methods. Test parameters included counting and identification of bacteria and fungi, and assessment of the remaining chlorine and pH level. Results: The results revealed that the average pH and chlorine levels were 7.8 and 1.62 mg/L, respectively. The isolated sample of bacteria included Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis. Other strains of bacteria, i.e. Bacillus cereus, Enterobacter faecalis, Enterobacter aerogenes, and Clostridium perfringens were reported negative. Of 21 strains sampled from five swimming pools in Shahrekord, Penicillium species with 9.52% percent, Candida albicans with 4.76 percent, and Aspergillus species with9.5 % were isolated. Conclusions: As public swimming pools can be contaminated with different types of parasites and also fungi, observing personal and environmental hygiene, and following standards for remaining free chlorine in water can help reduce the fungal contamination. Considering the fact that most of the bacteria isolated from the pool water in the study contained Escherichia coli, we can conclude that improving the environment and hygienic behavior of the swimmers can be effective in reducing the bacterial contamination in the pools.
Background: Urinary tract infection (UTI) is one of the most common bacterial diseases in outpatients and inpatients worldwide. Treatment of UTI has become challenging due to the emergence of pathogens with increasing resistance to antimicrobial agents.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.