Drinking 250 ml of diluted lemon juice accelerates the transit of tetrofosmin through the liver parenchyma and improves image quality on (99m)Tc-tetrafosmin myocardial SPECT.
We report the case of a 16-year-old male patient presenting with several mass lesions on the left side of his neck that had been there for weeks. Whole-body (18)F-fluorodeoxyglucose positron emission tomography and computed tomography ((18)F FDG PET-CT) revealed multiple focal areas of increased uptake of fluorodeoxyglucose (FDG) on the left side of the neck, left supraclavicular fossa, left axilla, and mediastinum, simulating the imaging findings of Hodgkin's lymphoma. Subsequent incisional biopsy of lymph nodes in the left supraclavicular fossa with histologic examination confirmed the diagnosis of Kimura disease. The differential diagnoses should include Kimura disease when evaluating regional or generalized lymphadenopathy seen on (18)F FDG PET-CT because it also may show prominent uptake of FDG.
A 76-year-old man with previous sigmoid colon resection for adenocarcinoma had low back pain for 2 months. Whole-body bone scintigraphy showed multiple focal Tc-99m methylene diphosphonate (MDP)-avid lesions in both rib cages and 3 lumbar vertebrae, indicating metastases. F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) imaging was performed for further evaluation of this possible metastatic disease and demonstrated the lumbar and costal metastases and several hypermetabolic areas in the pelvic bones, multiple thoracic vertebrae, both shoulders, and the right femur. Histopathologic examination of the right-sided iliac crest, however, revealed multiple myeloma.
Mediastinal lymphadenopathy is usually a sign of serious underlying disease. A patient who had nodular patchy opacity of the right hilum from a routine screening chest radiograph was referred for the whole-body PET/CT scan with FDG. The initial PET/CT scan demonstrated mediastinal lymphadenopathy and a 2-month follow-up PET/CT revealed the progression of lymphadenopathy with several newly developed FDG-avid nodes. Biopsy demonstrated chronic noncaseating granulomatous process, which was consistent with sarcoidosis. This report may suggest the possibility that rapid progression in size and FDG uptake of mediastinal nodes could be sarcoidosis and not malignancy.
Malignant struma ovarii is a rare disease in gynecology and the optimal treatment regimen for the tumor remains obscure. We present a patient who had malignant struma ovarii with peritoneal implants and pelvic structures and liver metastases shown on posttreatment iodine I-131 single-photon emission tomography (SPECT) and low-dose computed tomography (CT). The roles of I-131 ablation in the management of the disease are reviewed and discussed.
Metastatic pulmonary calcification (MPC) characterized by diffuse calcium deposition in the lungs is known to occur in patients with chronic renal failure. However, MPC with pulmonary artery calcification is uncommon and has only been detected in a few patients with severe disorders. A 48-year-old man with chronic renal failure had cough and progressive dyspnea. Ventilation-perfusion (V/Q) lung scans showed multiple large-sized mismatched V/Q defects in the left middle and lower zones of lungs, which was consistent with a high probability of pulmonary embolism (PE). The findings of pulmonary scintigraphy resulted from MPC with pulmonary artery calcification, revealed by simultaneous technetium-99m MDP scintigraphy, low-dose computed tomography, and high-resolution computed tomography (HRCT) of the chest.
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