An electrochemical glucose-sensing chip is developed based on a capillary-assembled microchip (CAs-CHIP) technique, which involves the simple assemblage of square capillaries possessing anti-interferential, glucose-sensing and electrochemical-detecting functions in poly(dimethylsiloxane) micro-channels.
A novel immunosensor is presented based on a charge accumulation system using an electrode modified with a polymer containing [osmium(4,4′-dimethyl-2,2′-bipyridine)2chloride]+/2+ and horseradish peroxidase (Os/HRP polymer) to detect N1,N12-diacetylspermine (DiAcSpm). Glucose oxidase (GOx)-labeled antibody captured with immunoreaction on Os/HRP polymer catalyzed the production of hydrogen peroxide, which oxidizes [Os(bpy)2Cl]+ in polymer with HRP. [Os(bpy)2Cl]2+ was gradually accumulated in the polymer and reduced back to [Os(bpy)2Cl]+ by applying −0.1 V. This accumulation system of redox species allows enhancement of the response.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.