The aim was to compare the effectiveness between patching and non-patching in the treatment of non-infected, non-contact lens related traumatic corneal abrasions, as well as of abrasions following foreign body removal. Materials and Methods: A prospective, controlled, randomized study on 100 patients over 1 year who presented with ocular pain, with a history of trauma or foreign body removal & had corneal abrasion on fluorescein stain. Patients were randomized into two groups: with patch group (receiving an eye patch with topical antibiotics) and no patch group (topical antibiotics with no eye patch) and patients were followed up. Results: Patients with corneal abrasions healed significantly faster and relieved symptomatically in the no patch group. Conclusion:We conclude that routine use of eye patching is not effective in the healing of simple corneal abrasion.
Cysticercosis, caused by the larval form of the pork tapeworm Taenia solium is potentially harmful disease with a variable clinical manifestation. The most commonly involved sites include eye, brain, bladder wall, and heart. Ocular cysticercosis can be extraocular or intraocular and may present with varied clinical symptoms. We report the case of extraocular cysticercosis in a 20 year old female presented with right exotropia, head tilting and painful right eye. CT-scan of right orbit showed bulky medial rectus with multiple ring enhancing lesions within the muscle, suggestive of cysticercosis. It becomes important to report this case because of the relative rarity of the condition, unusual site of the cyst i.e atypical involvement of medial rectus and the young age of the patient.
The aim of this study was to identify the ophthalmologic clinical features manifestations of facial nerve palsy patients.: In this observational study we have analyzed 50 eyes from 50 facial nerve palsy patients who were referred to our ophthalmic clinic. Ophthalmic drops, ointment were prescribed according to symptoms, taping was conducted in all eyes. 60% of the Bell’s palsy patients treated with prednisolone alone acyclovir-prednisolone (depending on the pathology) recovered within 5 months. An invasive procedure like temporary tarsorrhaphy was carried out in 5 patients permanent tarsorrhaphy in 3 patients. 2 patients underwent temporal bone decompression surgery. 3 patients developed corneal opacity with severe visual impairment despite surgical intervention, ophthalmic ointment, taping. Signs had improved in 75% of patients (lagophthalmos), 90% (corneal epithelium defect), 60% (epiphora). The ophthalmic clinical features of facial nerve palsy were mainly corneal lesion and eyelid malposition, and their clinical course improved after invasive procedures. The prognosis and ophthalmic signs were worse than in cases of simple facial palsy. Understanding these differences will help the ophthalmologist take care of patients with facial nerve palsy.
A B S T R A C T BACKGROUNDCorneal ulcer is a global burden which is an ocular emergency. The outcome of corneal ulcer depends on its management. Aetiology, microbiological flora and antibiotic sensitivity vary from region to region. We wanted to analyse the epidemiology of corneal ulcer in Barak valley region of Assam. METHODSThis is a cross-sectional study conducted from May 2017 to June 2018 at Silchar Medical College, Silchar, Assam, India. Cases of corneal ulcer in the study period were included. Corneal scrapping was done, and the sample was sent for Gram stain, KOH mount stain and culture-sensitivity testing. RESULTSA total of 122 patients were examined and 70 cases had positive microbiological findings. Pure bacterial isolates were found in 37 (52.8%) of the 70 cultures and pure fungal isolates in 23 (32.8%) of the cultures. Staphylococcus aureus was the most commonly isolated bacterial organism (42.5%). Out of fungal isolate, Aspergillus spp. (46.7%), was the commonest. Farmers were the most commonly affected work group. CONCLUSIONSAlthough the major aetiological agents in our study were bacterial, fungal ulcers were also seen in a significant proportion of patients. Staphylococcus was the major bacterial isolate and Aspergillus was the major fungal isolate.
Background Cisplatin is a frontline anticancer drug routinely used as part of concurrent chemoradiation administered at 3-weekly (100 mg/m2) dose. However, its role as fractionated weekly dose has achieved favorable outcome in patients with locally advanced squamous cell carcinoma of head and neck (LA-SCCHN) during induction chemotherapy (IC). We therefore sought to compare the toxicity outcomes of patients with LA-SCCHN treated with platinum-based IC at a single institution study using split-dose cisplatin chemotherapy. We compared the hematological and renal toxicity profile between the weekly cisplatin (30 mg/m2) (group A) versus 3-weekly (100 mg/m2) (group B) dosage schedule in this setting. Results The median age of the patients in groups A and B were 49.1 years and 48.27 years respectively with male:female ratio of 4:1. Most of the patients were of oropharyngeal cancers. Group A patients showed greater neutropenia (40.2%) than group B (20.6%). There was statistically significant fall in Hb% level in group A (13.9%) than in group B (11.9%). Renal profile showed greater rise in serum urea and serum creatinine (52.7%) in group B than in group A (52.29%) with statistically significant difference. Conclusions Since toxicities induced by high-dose cisplatin are irreversible and reduce quality of life in patients, the weekly regimen may be preferred owing to less renal toxicity, lesser hospitalization and more feasible in situations with high patient load and limited resources.
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