Oral keratinocytes had good biocompatibility with bladder acellular matrix grafts. Urethral reconstruction with these grafts was better than with bladder acellular matrix grafts alone.
Low carbon and digitalization are the general trends of manufacturing upgrading and transformation. Digital technology enables the whole process of green manufacturing and breaks down the spatial barrier. To achieve the dual carbon goals, the pressure-state-response (PSR) model, in which digital technology enables the green innovation of the manufacturing industry, was theoretically analyzed in this study. The measurement system of the digital green innovation (DGI) in the manufacturing industry was constructed according to the PSR framework. An evaluation model based on the analytic hierarchy process and the deviation maximization technique for order preference by similarity to an ideal solution method was constructed to measure the level of DGI. The results of this study from Chinese manufacturing are as follows. (i) The measurement system of the level of DGI in manufacturing industry includes a pressure system, state system and response system. (ii) In the past five years, the comprehensive index of the DGI in manufacturing industry has generally shown a trend of fluctuating rise. There are overall low and unbalanced phenomena in all regions. The gap decreased from 0.1320 to 0.1187, showing a gradually narrowing trend. (iii) Compared with other regions, the composite index of DGI is generally higher in the regions with a better ecological environment in the east and a more developed economy in the north. State parameters are higher than pressure and response parameters in most areas. (iv) Compared with other regions, the composite index of DGI in western and southern regions is lower, and the parameters of pressure, status and response are basically coordinated. (v) The application degree of digital technology, the emission intensity of waste water/exhaust gas of output value of one hundred million yuan and the expenditure intensity of digital technology adopted by enterprises are the key influencing factors of DGI in the manufacturing industry. This study not only proposed an evaluation index system of the digital green innovation level, but also puts forward policy guidance and practical guidance of digital technology to accelerate the green and intelligent manufacturing industry.
BackgroundCambodia, a lower middle-income country of about 16 million individuals in southeast Asia, endures a high burden of both tuberculosis and other lower respiratory infections. Differentiating tuberculosis from other causes of respiratory infection has important clinical implications yet may be challenging to accomplish in the absence of diagnostic microbiology facilities. Furthermore, co-infection of tuberculosis with other bacterial lower respiratory infections may occur. The objective of this study was to determine the prevalence and etiologies of tuberculosis and other bacterial co-infection and to analyze the clinical and radiographic characteristics of patients presenting with respiratory infection to a provincial referral hospital in Cambodia.MethodsWe performed a retrospective, cross-sectional analysis of laboratory and clinical data, on patients presenting with respiratory symptoms to a chest clinic of a 260-bed provincial referral hospital in Cambodia. We analyzed mycobacterial and bacterial sputum test results, and demographics, medical history and chest radiography.ResultsAmong 137 patients whose treating clinicians ordered sputum testing for tuberculosis and other bacteria, the median age was 52 years, 54% were male, 3% had HIV infection, and 26% were current smokers. Nearly all had chronic respiratory symptoms (> 96%) and abnormal chest radiographs (87%). Sputum testing was positive for tuberculosis in 40 patients (30%) and for bacteria in 60 patients (44%); 13 had tuberculosis and bacterial co-infection (9% overall; 33% of tuberculosis patients). Clinical characteristics were generally similar across pulmonary infection types, although co-infection was identified in 43% of patients with one or more cavitary lesions on chest radiography. Among those with bacterial growth on sputum culture, Gram negative bacilli (Klebsiella and Pseudomonas spp.) were the most commonly isolated.ConclusionsAmong patients with symptoms of respiratory infections whose treating clinicians ordered sputum testing for tuberculosis and other bacteria, 9% of all patients and 33% of tuberculosis patients had tuberculosis and bacterial co-infection. Greater availability of microbiologic diagnostics for pulmonary tuberculosis and bacterial infection is critical to ensure appropriate diagnosis and management.
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