The article presents the results of a study of a polyphenolic extract of the herb Eupatorium cannabinum L., which grows on the territory of the Krasnodar Territory. The aim of the study was to conduct a phytochemical analysis of the BAS of a dry extract of Eupatorium cannabinum L. and determination of its antioxidant activity. Thus, as a result of the conducted studies, it was found that a diverse composition of phenolic compounds is identified in the dry extract of Eupatorium cannabinum L., among which the presence of rutin, quercetin salicylic, chlorogenic, caffeic, ferulic, π-coumaric and gallic acids was revealed. It was found that the content of phenolic carboxylic acids in the dry extract of Eupatorium cannabinum L. averaged 15.10%, flavonoids – 4.34%. The results of the studies conducted on the in vitro model system revealed the ability of the dry extract of Eupatorium cannabinum L. reduce the accumulation of Fe2+-induced POL products, which indicates the presence of direct antioxidant action. The mechanism of action of the resulting extraction product on the one hand may be related to the ability of phenolic compounds that make up the dry extract to act as free radical traps and restore reactive oxygen species, on the other hand, the resulting extract can act as chelators of Fe2+ ions, which significantly reduces the rate of free radical processes. The obtained data complement the previously discovered information about the antimicrobial effect of the dry extract of the cannabis herb and allow us to predict the potential effectiveness of the use of drugs based on it for the treatment of infectious and inflammatory skin diseases due to the presence of combined antimicrobial and antioxidant effects.
The paper deals with topical issues of developing additional professional advanced training programs for specialists in several specialties with a secondary pharmaceutical and medical education. For many years, postgraduate medical and pharmaceutical education provided for a one-time advanced training of specialists over a five-year period. At the same time, such a training format lasting, as a rule, 144 hours, hardly allowed the student to master a significant amount of relevant professional information accumulated by science and practice over the past five years. It is obvious that the current pace of development of domestic healthcare in general and pharmacy, in particular, the emergence and active use of innovative educational technologies, the existing need for pharmaceutical personnel to regularly receive updated and systematized professional knowledge could not but lead to the transformation of the previously existing model of postgraduate education. However, to date, two inextricably linked components of this process have been clearly defined: the introduction of continuing medical and pharmaceutical education and the accreditation of specialists. Moreover, in the current conditions, continuous education is becoming a necessary condition for the formation of a portfolio and admission to the accreditation procedure for a specialist, while accreditation serves as a fundamental licensing tool for professional activities. An active participant in the continuing medical and pharmaceutical education system are educational organizations that have been delegated the functions of developing and implementing additional professional advanced training programs. The purpose of this work was to popularize the experience of the Department of Pharmacy of the Kuban State Medical University of the Ministry of Health of Russia in the development of additional educational programs for specialists with medical and pharmaceutical education. The methodological basis for the process of developing a development of additional educational programs for specialists with medical and pharmaceutical education was the professional competencies presented in the Federal State Educational Standards in the specialty "Pharmacy", Nursing, Federal State Educational Standards "General Medicine", Federal State Educational Standards "Obstetrics" and labor functions given in the relevant professional standards. On the example of additional professional advanced training programs developed at the Department of Pharmacy of the Kuban State Medical University of the Ministry of Health of Russia, modern approaches are shown that allow harmonizing their content with the requirements of the Federal State Educational Standards for medical and pharmaceutical specialties with professional standards "Pharmacist", "Nursing Organization Specialist", "Nurse/Nurse Brother", "Midwife", "Nurse Anesthetist", "Paramedic".
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