The interaction between (1,1'-binaphthalene)-2,2'-diol (BINOL) and lecithin liposome was studied by UV-Vis, fluorescence and 1 H NMR spectroscopies. BINOL can obviously associate with lecithin liposome and the preferential binding site of BINOL with lecithin liposome is located in the headgroup region. The hydrogen bond and electrostatic interaction should exist in BINOL/liposome system, which restricts intra-annular rotation of naphthol moieties. Therefore, the fluorescence intensity of BINOL increases when a small quantity of liposome is added into the system. The partition coefficient K D between the lecithin liposome and the aqueous phase is 310.9. With the increase of BINOL concentration, the micropolarity (I 1 /I 3 ) and membrane fluidity of liposome decreased, while the viscosity of membrane increased.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.