PurposeThe properties of materials under impact load are introduced in terms of metal, nonmetallic materials and composite materials. And the application of impact load research in biological fields is also mentioned. The current hot research topics and achievements in this field are summarized. In addition, some problems in theoretical modeling and testing of the mechanical properties of materials are discussed.Design/methodology/approachThe situation of materials under impact load is of great significance to show the mechanical performance. The performance of various materials under impact load is different, and there are many research methods. It is affected by some kinds of factors, such as the temperature, the gap and the speed of load.FindingsThe research on mechanical properties of materials under impact load has the characteristics as fellow. It is difficult to build the theoretical model, verify by experiment and analyze the data accumulation.Originality/valueThis review provides a reference for further study of material properties.

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The basic unit in life is cell. It contains many protein molecules located at its different organelles. The growth and reproduction of a cell as well as most of its other biological functions are performed via these proteins. But proteins in different organelles or subcellular locations have different functions. Facing the avalanche of protein sequences generated in the postgenomic age, we are challenged to develop high throughput tools for identifying the subcellular localization of proteins based on their sequence information alone. Although considerable efforts have been made in this regard, the problem is far apart from being solved yet. Most existing methods can be used to deal with single-location proteins only. Actually, proteins with multi-locations may have some special biological functions that are particularly important for drug targets. Using the ML-GKR (Multi-Label Gaussian Kernel Regression) method, we developed a new predictor called "pLoc-mGpos" by in-depth extracting the key information from GO (Gene Ontology) into the Chou's general PseAAC (Pseudo Amino Acid Composition) for predicting the subcellular localization of Gram-positive bacterial proteins with both single and multiple location sites. Rigorous cross-validation on a same stringent benchmark dataset indicated that the proposed pLoc-mGpos predictor is remarkably superior to "iLoc-Gpos", the state-of-the-art predictor for the same purpose. To maximize the convenience of most experimental scientists, a user-friendly web-server for the new powerful predictor has been established at Natural Science http://www.jci-bioinfo.cn/pLoc-mGpos/, by which users can easily get their desired results without the need to go through the complicated mathematics involved.

To further study the law of strength degradation, the residual strength degradation model is established based on the definition of fatigue damage, considering the interaction of various uncertain factors and time factors in service environment. Combined with equivalent damage model, a nonlinear cumulative damage model is proposed, which takes the interaction among loading loads into account and improves the accuracy of calculation. Additionally, the equivalent transformation of multistage load is studied using interval theory. According to the interval dynamic nonprobability reliability prediction model, a dynamic reliability analysis of the interval model is carried out. Dynamic reliability of the component is analyzed under multistage load accumulation damage to verify the effectiveness of the method.