BACKGROUND: There is limited data on the spectrum of benign and malignant neoplasms of skin and subcutis in India. AIM: This study was undertaken in a tertiary care hospital of Uttarakhand to evaluate the frequency of various neoplasms affecting skin and subcutis in biopsy specimens. MATERIAL AND METHODS: A retrospective and prospective analysis of 660 skin biopsies was undertaken. The neoplasms were categorized as per International classification of World health Organization (WHO). RESULTS: Of all the skin biopsies analyzed, tumors were seen in 24.5% (162/660). Benign neoplasms were more frequently seen (72.8 %) than malignant neoplasms (27.2%). Benign to malignant ratio was 2.7:1. Amongst the benign neoplasms, soft tissue tumors including vascular, fibrous/ fibrohistiocytic, lipomatous and neural tumors constituted the largest group (61.2%) followed by appendageal tumors (22.0%), melanocytic naevi (12.3%) and keratinocytic tumors (5.1%). On the other hand, amongst the malignant neoplasms, keratinocytic tumors were the commonest (77.3%) followed by melanoma (9.1%) and appendageal tumors (9.1%). CONCLUSION: Soft tissue tumors of skin and subcutis form the largest group amongst the benign neoplasms and keratinocytic tumors are the commonest malignant skin tumors.
Soft tissue chondroma is a rare benign, slow growing tumor usually located in hand and foot. Scrotal chondroma is exceedingly rare; chondromas in the pelvic region have also been reported. However, chondroma occurring in the scrotal wall is extremely rare, and only a few cases have been reported worldwide. They should be differentiated from well-differentiated chondrosarcoma. To the best of our knowledge, this is the first case of scrotal chondroma to be reported from India.
The entities under Interface Dermatitis (IFD) have variable clinical pattern and distribution which makes the diagnosis difficult.Basal cell vacuolar degeneration, leucocytic inflammatory infiltrate at DEJ, pigment incontinence and presence of melanophages are the most common histopathological findings in IFD.A combination of proper clinical observation and histopathological study gives a conclusive diagnosis that helps in predicting the course of disease and its management.Although the prototypic skin disease for IFD is Lichen Planus (LP) , there are many other conditions which can produce lichenoid dermatitis as a part of their histological presentation. Thus, the group of diseases included in
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