AIMS:The purpose of this study is to investigate the effect of improved periodontal health on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have generalized periodontitis.MATERIALS AND METHODS:A total of 45 type 2 DM patients with generalized periodontitis were selected for the study. The selected patients were randomly assigned to three groups (groups A, B, and C) comprising 15 patients each: • Group A received treatment with scaling and root planing only. • Group B received treatment with scaling and root planing followed by systemic doxycycline. • Group C received no treatment (control group). The periodontal parameters recorded included plaque index, gingival index, probing pocket depth, and clinical attachment level. These parameters were recorded at baseline (day zero), at 1 month, and at the end of 3 months. The following metabolic parameters were recorded: fasting blood glucose (FBG), postprandial blood glucose (PPBG), and glycated hemoglobin. These were recorded at baseline (day zero) and at the end of 3 months.STATISTICAL ANALYSIS:All the parameters were subjected to repeated-measures ANOVA and Scheffe's post hoc test.RESULTS:A statistically significant effect could be demonstrated for periodontal parameters for both group A and group B (treatment groups). Glycated hemoglobin values showed statistically significant decrease in treatment groups compared to the control group, with group B showing more significant decrease than group A.CONCLUSIONS:The results of this study showed that nonsurgical periodontal treatment is associated with improved glycemic control in type 2 DM patients.

Our results showed significant improvement in wound size and epithelial healing after topical ozonated oil application compared to control oil on palatal wounds.

The adjunctive use of PRF to conventional OFD may be potentially used in the treatment of intrabony defects.

Objective: The present study was undertaken to assess the therapeutic effects of topical ozonated oil on early healing of free gingival graft surgical sites. Study Design: Twenty subjects were entered into this triple-blinded, randomized, placebo-controlled clinical trial, designed to evaluate the efficacy of ozonated oil on free gingival graft surgical wounds. Subjects were assigned to either the ozone group, in which ozonated oil was applied to the surgical wound, or the control group, in which non-ozonated oil was used as a control. Patients were postoperatively evaluated by cytological analysis. Cytological analysis consisted of the keratinisation and superficial cell indices measured at baseline, after 24 h, on the 3rd, 7th, 14th and 21st day and 2, 3, 8 and 18 months postoperatively. Results: Cytological results showed that there was a significant (p < 0.001) improvement in epithelial healing by the 7th, 14th and 21st day and 2, 3 and 8 months postoperatively in the ozone group compared to the control group. Conclusion: The present study showed significant improvement in epithelial healing and gingival health after topical application of ozone-treated plant oil to gingival surgical sites.