The National Library of Medicine's (NLM) Division of Specialized Information Services (SIS) Toxicology and Environmental Health Information Program is responsible for the management of the online Hazardous Substances Data Bank (HSDB). HSDB, a part of NLM's Toxicology Data Network (TOXNET ® ), is a file of chemical/substance information with one record for each specific chemical or substance, or for a category of chemicals or substances. Like the rest of TOXNET's databases and other resources, HSDB is available online at no cost to global users. HSDB has approximately 5,600 chemicals and substances, with a focus on toxicology information and also on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas of likely interest to HSDB users. All data are from a core set of books, government documents, technical reports, selected primary journal literature, and other online sources of information, with a goal of linking the HSDB content to as much publicly available information as possible. HSDB's content is peer-reviewed by a Scientific Review Panel of experts covering the scope of HSDB content. Recent enhancements include the addition of chemical structures to HSDB records, the addition of new subfields such as age groups for human data, more occupational exposure standards, and the addition of information on numerous nanomaterials. Examples of future plans include providing more exposure-related information, e.g., uses of a chemical or substance in consumer products; the addition of information summaries aimed towards consumers and other members of the public wanting to learn about a chemical or substance; more visual content such as diagrams (images) of the pathways of metabolism of a substance; and enhanced search features and navigation.
A 19-year-old female volleyball player reported shoulder pain, numbness, tingling, and difficulty gripping in her left arm. Provocation tests were positive for thoracic outlet syndrome (TOS). Duplex ultrasonography revealed occlusion of the subclavian artery. The athlete underwent a first rib resection and scalenectomy. A cervical rib and 75% of the first rib were excised. Rehabilitation consisted of regaining range of motion and strength. Return to play occurred after 14 weeks of rehabilitation. Thoracic outlet syndrome is rare and often misdiagnosed. All sports medicine professionals should have an understanding of TOS symptoms and path to diagnosis.
Metabolic syndrome (MetS) reflects a combination of physiological and metabolic abnormalities which increases an individual's risk for developing cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Components of MetS include abdominal obesity, triglycerides, HDL cholesterol, blood pressure and fasting glucose levels. The Adult Treatment Panel III (ATP III) criteria for MetS is met when an individual displays three of the five components greater than established values.
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