Ru(ii)-Catalyzed C–H alkenylation/cyclization and Ir(iii)-catalyzed C–H sulfamidation provided indol-3-one derivatives and sulfamidated 2-phenylisatogens respectively, with good yields and excellent functional group tolerance.
An efficient protocol by Rh-catalyzed direct C–H vinylation of 2-arylpyridines with a commercially available and air-stable potassium vinyl donor has been developed. This method affords the corresponding pyridinyl styrene derivative with moderate to excellent yields under mild conditions, which is extremely beneficial to the total synthesis of the natural product palmatine.
A Co(II)-mediated decarboxylative/desilylative CÀ H activation/ annulation reaction for the efficient synthesis of 3-arylisoquinolines has been developed. Using alkynyl carboxylic acid and alkynyl silane as terminal alkyne precursors, providing straightforward routes for the synthesis of natural alkaloids and novel structural analogues.
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