Objective: To determine the prevalence of asymptomatic bacteriuria in pregnant women and antimicrobial susceptibility pattern of pathogens isolated and also to determine the relationship between asymptomatic bacteriuria and pyuria. Methods: A total of 392 urine specimens were collected from 392 pregnant women with asymptomatic bacteriuria attending different antenatal care clinics for regular perinatal care between April, 2007 and July, 2008. All specimens were processed using standard microbiological procedures. All the subjects were evaluated for bacteriuria. Results: The prevalence of asymptomatic bacteriuria was 6.1% among the pregnant women in Srinagar. From 92 (23.5%) patients who had ≥5 pus cells per high power field, only 15 (16.3%) had positive urine culture. E.coli (~71%) was the commonest causative agent of asymptomatic bacteriuria followed by Klebsiella pneumoniae (~17%), group B Beta haemolytic Streptococcus (8.3%) and Proteus mirabilis (4.2%). Ciprofloxacin was found to be highly sensitive against all isolates. Conclusion: Screening of bacteriuria in pregnancy and proper treatment must be considered as an essential part of antenatal care in this community. To prevent asymptomatic bacteriuria complications, all pregnant women should be screened at the first antenatal visit. A negative test for pyuria is not a reliable
Pseudomonas aeruginosa is one of the most common gram-negative bacteria. identified in the clinical specimens of hospital admitted patients. A major problem in P. aeruginosa infection may be that this pathogen exhibits a high degree of resistance to a broad spectrum of antibiotics. The study aimed to isolate and determine the antimicrobial susceptibility patterns of the P. aeruginosa. This prospective study was done over a period of six months. Forty one clinical isolates of Pseudomonas aeruginosa (P. aeruginosa) were isolated from sputum specimens of the patients suspected of having respiratory tract infection. The antibiotic susceptibility profiles of all the isolates were determined using disk diffusion method as recommended by Clinical Laboratory Standards Institute. Ciprofloxacin was found to be the most effective antimicrobial agent with 85.4% susceptibility followed by imipenem (75.6%), aminoglycosides (amikacin, 95.1% and gentamicin, 90.3%), and the beta-lactams (cefepime 65.8%, ceftazidime, 51.2%). Piperacillin showed the maximum resistance (46.3%) followed by Aztreonam (36.6%). Regular antimicrobial susceptibility surveillance is essential for area-wise monitoring of the resistance patterns. An effective national and state level antibiotic policy and draft guidelines should be introduced to preserve the effectiveness of antibiotics and for better patient management. DOI: http://dx.doi.org/10.3329/bjms.v13i1.17428 Bangladesh Journal of Medical Science Vol. 13 No. 01 January2014: 45-48. Table I & Figure I added on 02 February 2014.
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