Eighty-three confirmed cases of neurocysticercosis diagnosed as per modified delBrutto criteria were enrolled in the study (Group-I) to observe cognitive and behavioural changes. Controls consisted of two groups: children with idiopathic generalized tonic-clonic seizure (Group-II) and normal children with non-specific cough (Group-III). Cases and controls were subjected to cognitive and behaviour assessment. There was significant difference in the intelligence quotient (IQ) of cases in domains of visual perception, immediate recall, analysis synthesis and reasoning, verbal ability, memory and spatial ability. In the age group of 6-18 years, cases had significantly more behaviour problems than control without seizure, in domains of anxious depressed, withdrawn depressed, somatic problems, social problems and rule-breaking behaviour. Neurocysticercosis causes decline in cognitive function and behaviours in older children, which should be recognized early for appropriate management and to avoid undue parental anxiety.
Fatigue is almost a common problem often reported by the cancer patients that severely affects all aspects of quality of life. Prevalence of cancer related fatigue ranges from 50% to 90% of cancer patients overall. After addressing treatable contributing factors, such as hypothyroidism, anemia, insomnia, pain, emotional distress, medication adverse effects, metabolic disturbances, or organ dysfunction such as heart failure, myopathy, and pulmonary fibrosis, patients may be screened with a short fatigue assessment tool. There is a pressure for pharmacologic therapy to shift away from reliance on opioids and ineffective procedures toward comprehensive cancer related fatigue (CRF) management that includes evidence-based nonpharmacologic options. This review details the magnitude of the current CRF problem including its impact on quality of life as well as the challenges of CRF management for patients and a healthcare workforce engaging prevalent strategies not entirely based in current evidence. Transforming the current system of CRF care to a responsive comprehensive model necessitates those options for treatment and collaborative care must be evidence-based and include effective nonpharmacologic strategies that have the advantage of reduced risks of adverse events and addiction liability. Patients with cancer related fatigue may benefit from self-administrable nonpharmacological interventions without any side effects. Health care personnel often have insufficient knowledge about fatigue and its treatments or underestimate the impact of fatigue on quality of life. A practical review may be useful to health care professionals in order to identify the cancer related fatigue during the early period of cancer process and treat it effectively to improve the quality of life which contribute to the positive outcomes in cancer clients. Therefore, the main purpose of this review is to analyze the possible nonpharmacological approach to manage cancer related fatigue and recommend future research that will clarify these approaches and facilitate the formulation of new treatment options.
Ischemic infarction in scorpion sting envenomation is rare and only few cases have been reported in adults. A 3-y-old child is reported who developed recurrent generalized tonic-clonic seizures 2 h after admission and hemiparesis on third day of admission following scorpion sting. Cranial tomography showed infarction in right and left frontoparietal lobes. The child was managed conservatively with prazosin, lorazepam and phenytoin sodium and made a complete recovery.
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