Experientia 39 (1983), Birkh~user Verlag, CH-4010 Basel/Switzerland others !~ as an antidote for heavy metal toxicity. As shown in table 1, the minimal effective dose of selenium which significantly prolongs the duration of pentobarbital hypnosis was 2.4 mg/kg. In the next experiment the time-course of selenium-induced prolongation of hypnosis was examined. The animals were treated with selenium (2.4 mg/kg) and challenged at various time periods thereafter. The results of this experiment are shown in table 2. Although the duration of hypnosis was increased at 48 h, a significant prolongation of pentobarbital hypnosis was first observed at 72 h.This prolongation of effect was also observed at 96 h, the last time period examined. Thus, the effect of selenium on drug response does not occur immediately, but requires approximately 48-72 h to develop.Discussion. The results of the present study indicate that
The taxonomic status of Flacourtia jungomas (Lour.) Raeus. has been discussed together with its nutraceutical importance and the important biochemicals isolated there from. The ripe fruits have high fiber content together with good protein content, low fat and higher amount of monosaturated fatty acids as compared to polysaturated fatty acids. It contains significant amount of β-carotene followed by rutein + zeaxanthene, retinol and phylloquinone (Vit K) which are important in the regulation of haemoglobin and fibrinogen in human body. Besides these, ascorbic avid (Vit. C) and niacin are also present in significant amounts. Ripe fruits contain good amount of potassium which has a definite role in regulation of blood pressure followed by phosphorus and magnesium having their role in controlling osteoporosis. [Medicinal Plants 2009; 1(1) : 49-53].
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