Background & Objective(s): Emotional and behavioral problems among adolescents represent a considerable public health problem in developing countries. These problems are considered a source of stress for adolescents as well as their families, schools and community. Emotional health and wellbeing of young people have implications on their self-esteem, behavior, school attendance, educational achievement, social cohesion and future health and life chances. To estimate the prevalence of emotional and behavioral problems and to determine the association between these problems and socio-demographic variables among adolescent students in Assiut district. Methods: A cross sectional study was conducted in randomly selected secondary schools (2 urban and 2 rural) in Assiut district, and 400 students were included in the study. Self-administered questionnaires were used to collect study data which included: personal data, socioeconomic status scale and self-reported version of Strengths and Difficulties Questionnaire (SDQ) (Arabic version) which included 25 items divided into 5 subscales (conduct problems, hyperactivity, emotional symptoms, peer problems and prosocial behavior) Results: About 45 % of adolescents were identified with emotional and/or behavioral problems using the SDQ. These problems included conduct, emotional, peer problems, prosocial and hyperactivity difficulties (36.0%, 42.3%, 5.0%, 28.5% and 24.8% respectively). Emotional difficulties were significantly higher (p value= 0.02) among females (40.4%), while conduct difficulties were more prevalent among males (47.5%). The majority of students with emotional/ behavioral problems (90%) reported high negative impact of such problems that was significantly associated with female sex, rural residents, students of low socioeconomic level and whose mothers were housewives. Conclusion: Screening secondary school adolescents in Assiut district revealed high prevalence of emotional and behavioral problems that was associated with perceived enormous negative impact. Further studies and intervention programs are greatly needed to address adolescent mental health needs.
Naproxen is a nonsteroidal anti-inflammatory drug which shows variable absorption and bioavailability due to its poor solubility. In this study we aimed to improve the dissolution rate of the drug by solvent deposition onto certain adsorbents including porous silica, Avicel and Bentonite. Physical mixtures of naproxen with the investigated adsorbents were also prepared. The molecular behavior of naproxen in the investigated systems were studied using infrared absorption spectra, differential scanning calorimetry and X-ray diffraction analysis. The dissolution rate of the drug was also investigated. The obtained results indicated that naproxen was transformed to the amorphous state in case of mixtures loaded with porous silica. This transformation resulted in a significant enhancement of the dissolution rates of the drug. In addition, it was noticed that, the drug: adsorbents weight ratio of the prepared mixtures influenced the drug dissolution rate enhancement. Accordingly, it can be concluded that, by increasing the weight ratio of the used adsorbent in the mixture, the larger the enhancement in the dissolution rate of naproxen will be obtained.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.