Objective: To compare the outcome of expectant management versus immediate delivery in females with preterm premature rupture of membrane close to term. Study Design: Randomized controlled trial Place and Duration of Study: Department of Obstetrics & Gynaecology Unit III, Fatima Memorial Hospital Lahore from 20th June 2018 to 20th December 2018 Methodology: Three hundred females were included through emergency. They were divided in two groups; females of group A managed conservatively and females of group B were induced for delivery and immediate delivery was conducted. After delivery in both groups, outcome was recorded i.e. neonatal distress, poor Apgar score or NICU admission. Results: The mean age of group A was 27.53±4.99 years and group B was 25.81±4.92 years. The mean gestational age of group A was 33.92±1.41 weeks and group B was 33.88±1.40 weeks. In group A there were 28 (18.7%) women with parity 1, 40(26.7%) with parity 2, 42 (28%) with parity 3 and 40 (26.7%) with parity 4 whereas in group B there were 28(18.7%) women with parity 1, 40 (26.7%) with parity 2, 42 (28%) with parity 3 and 40 (26.7%) with parity 4. In group A there were 54 (36%) women with normal BMI, 44 (29.9%) were overweight and 52 (34.7%) were obese while in group B there were 63 (42%) women with normal BMI, 38 (25.3%) were overweight and 49 (32.7%) were obese. There was no significant (P=0.329) association between neonatal distress and study groups and also no significant (P=0.202) association between poor APGAR score and study groups. Conclusion: Incidence and rate of neonatal distress in complicated pregnancies by PPROM within 34 and 37 weeks of gestation is very low Keywords: Delivery, Preterm, Premature, Rupture of membrane, Term, Outcome, Expectant, Management
Introduction: Abnormal uterine bleeding is one of the commonest issues in perimenopausal age group. The proportion is 9-30% in reproductive age group. This extent rises to 70% in perimenopausal and postmenopausal women’s. Irregular uterine dying (AUB) warrants an intensive assessment in perimenopausal females and subsequently it’s vital to perform it in a cost-effective way with available resources. Objective: To compare the efficacy of Hysteroscopic guided biopsy and endometrial cytology To find out the efficacy of endometrial cytology in detecting different normal and abnormal endometrial patterns Study design & Settings: It is a prospective comparative study conducted at Social Security Hospital, Multan Road, Lahore included patients 30 years and above with the chief complaints of abnormal uterine bleeding. Study Duration: 01 year January 2020 to December 2020 Sample: 100 patients Inclusion Exclusion Criteria: Females having symptoms of abnormal uterine bleeding and age above than 30 years are included in the study. The females who are pregnant and having infection or malignancy are excluded from the research Results: This Planned comparative hospital-based study was done in one hundred patients with abnormal uterine bleeding taken after the informed consent, inclusion and exclusion criteria. Endometrial thickness was assessed and all cases with <5 mm thickness will be avoided from the study. Mean age of the patient was found 45 and standard deviation 7.43. Practical implication Conclusion: To get the endometrial sample by pipelle technique is a safe procedure. It has high specificity, sensitivity, positive and negative predictive values when compared to hysteroscopy. In this way, to obtain adequate endometrial sample, Pipelle biopsy should be considered as important way of investigation. Keywords: Abnormal uterine bleeding, Pipelle, Endometerial sampling, FIGO
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