Background: Coronavirus disease 2019 (COVID-19) has become a global health threat, and thus, an early and effective set of predictors is needed to manage the course of the disease. Objectives: We aim to determine the effect of SARS-CoV-2 on lipid profile and to evaluate whether the atherogenic index of plasma (AIP) could be used to predict in-hospital mortality in COVID-19 patients. Methods: In this retrospective chart review study, a total of 139 confirmed COVID-19 patients, whose diagnoses are confirmed by PCR and computerized tomography results, are enrolled. The study population is divided into two groups: the deceased patient group and the survivor group. For each patient, fasting total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and the triglyceride values are obtained from the laboratory tests required at the admission to hospital. Finally, the AIP is calculated as the base 10 logarithm of the triglyceride to HDL-C ratio. Distributional normality of the data is checked and depending on the normality of the data, either T test or Mann Whithey U test is employed to compare the two aforementioned study groups. Results: Mean age of the study population is 49.2 § 20.8 and 61.2% (n = 85) is male. Out of the 139 patients 26 have deceased and the remaining 113 patients survived the disease. Mean age of the deceased patients was 71.8*8.9 and mean age of the survivor patients is 44.0*19.2 (p < 0.001). The deceased group had more patients with hypertension (50.0% vs. 23.0, p = 0.006), diabetes mellitus (35.6% vs. 10.6%, p = 0.002), cardiovascular diseases (23.1% vs. 4.4%, p = 0.001), chronic renal insufficiency (11.5% vs. 0.9%, p = 0.003) and atrial fibrillation (7.7% vs 0%, p = 0.003). The AIP values in the deceased group are found to be statistically higher (p < 0.001) than the survivor group. As a measure of mortality, the area under the operating characteristic curve for the AIP is calculated as 0.850 (95% confidence interval: 0.772À0.928) along with the optimal cutoff value of 0.6285 (78.6% sensitivity and 80.5% specificity). Furthermore, the AIP value is observed to be elevated in patients with pneumonia, intubation history, and intensive care admission during hospital stay (p = 0.002, p < 0.001 and p < 0.001, respectively). Finally, compared to the survivor group, total cholesterol, HDL-C, LDL-C values are lower (p = 0.004, p < 0.001 and p < 0.001, respectively) and triglyceride levels are higher (p < 0.001) in deceased patients. Conclusion: In this study, we show that the AIP levels higher than 0.6285 can predict in-hospital mortality for COVID-19 patients. Moreover, the AIP emerges as a good candidate to be used as an early biomarker to predict pneumonia, intubation and intensive care need. Hence, regular check of the AIP levels in COVID-19 patients can improve management of these patients and prevent deterioration of the disease.
SUMMARYObjectivesDetermining the properties of patients admitted to the emergency department (ED) is important to plan for future and quality assurance. In this study, we aimed to evaluate the properties of patients admitted to our ED to improve the quality of care within our hospital.MethodsIn the study period, the patients: (i) who have their full information in hospital information and management system (HIMS) and (ii) older than 17 years of age were included into the study. Demographic information, admission and discharge rates, mean staying time in the ED, triage categories, International Classification of Diseases – 10 (ICD-10) diagnoses were evaluated.ResultsDuring the study period, 32,117 cases were seen by the ED. However, 22,955 patients (71.4%) had complete information in the HIMS. The mean age was 44.92±19.50 and female gender was found 52.2%. The patients who were located in 18–29 age group was the major group of all cases (30.8%). Emergent and urgent cases were 26.1% and 14.8%, respectively. Non-urgent cases were also found (59.1%). The mean age of patients located in the emergent group (55.19±18.59) were significantly higher than urgent and non-urgent group (p≤0.01). The highest patient volume was seen on Sunday, between 20:00 and 22:00 o'clock. The mean staying time in the ED was 183.6 minutes and the admission rate was 17.6%. The three most noted ICD-10 codes were respiratory (16.6%), gastrointestinal (11.3%), musculoskeletal (11.2%) codes.ConclusionsThe data that was correctly uploaded into the system did not reach our expectation. Data can be more appropriately uploaded by medical secretaries. Registering patient information in a digital atmosphere while performing analyses will undoubtedly have an effect on future focused studies.
BACKGROUND: Pneumothorax (PNX) is the collection of air between parietal and visceral pleura, and collapsed lung develops as a complication of the trapped air. PNX is likely to develop spontaneously in people with risk factors. However, it is mostly seen with blunt or penetrating trauma. Diagnosis is generally confirmed by chest radiography [posteroanterior chest radiography (PACR)]. Chest ultrasound (US) is also a promising technique for the detection of PNX in trauma patients. There is not much literature on the evaluation of blunt thoracic trauma (BTT) and pneumothorax (PNX) in the emergency department (ED). The aim of this study was to investigate the effectiveness of chest US for the diagnosis of PNX in patients presenting to ED with BTT
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