Solar ultraviolet (UV) radiation is the second most prevalent carcinogenic exposure in Canada and is similarly important in other countries with large Caucasian populations. The objective of this article was to estimate the economic burden associated with newly diagnosed non-melanoma skin cancers (NMSCs) attributable to occupational solar radiation exposure. Key cost categories considered were direct costs (healthcare costs, out-of-pocket costs (OOPCs), and informal caregiver costs); indirect costs (productivity/output costs and home production costs); and intangible costs (monetary value of the loss of health-related quality of life (HRQoL)). To generate the burden estimates, we used secondary data from multiple sources applied to computational methods developed from an extensive review of the literature. An estimated 2,846 (5.3%) of the 53,696 newly diagnosed cases of basal cell carcinoma (BCC) and 1,710 (9.2%) of the 18,549 newly diagnosed cases of squamous cell carcinoma (SCC) in 2011 in Canada were attributable to occupational solar radiation exposure. The combined total for direct and indirect costs of occupational NMSC cases is $28.9 million ($15.9 million for BCC and $13.0 million for SCC), and for intangible costs is $5.7 million ($0.6 million for BCC and $5.1 million for SCC). On a per-case basis, the total costs are $5,670 for BCC and $10,555 for SCC. The higher per-case cost for SCC is largely a result of a lower survival rate, and hence higher indirect and intangible costs. Our estimates can be used to raise awareness of occupational solar UV exposure as an important causal factor in NMSCs and can highlight the importance of occupational BCC and SCC among other occupational cancers.
Background:As glass ionomers have the ability to reload fluoride from outside sources, the aim was to compare the recharge pattern of six glass ionomer cements after exposure to fluoride.Materials and Methods:Fuji VII, Fuji IX, Riva Pink, Riva Bleach, Ketac Fil and Fuji IX Extra were investigated. The fluoride-containing materials used were tooth paste and mouth wash (Colgate). Specimens of each material (n=15) were immersed separately in deionized water for 59 days. Then the samples of each material were divided into three groups of five each. Two groups were recharged for 2, 20 and 60 min daily during three consecutive weekly intervals and then no treatment for one week. The third group was used as control. Fluoride release measurements (μg/cm2/day) were made in every 24 h. One-way and repeated measures analysis of variance tests were used.Results:Tooth paste recharged materials showed higher level of recharge. On day 1, the difference of fluoride release from different treatment groups of different materials except for Fuji IX Extra were not significant (P>0.05). On days 7 and 14, the differences observed were significant (P<0.05) for all materials except for Fuji VII (tooth paste versus mouth wash) and Trial Fuji IX (mouth wash versus control) and on day 14 for Rvia Pink (mouth wash versus control). On days 21 and 28, the differences observed were significant for all the materials (P<0.05) except for Riva Pink (toothpaste versus mouth wash), Riva Bleach, Ketac Fil and Trial FujiI X (mouth wash versus control) on day 28.Conclusion:A time tabled schedule of application of fluoride-containing materials could help to achieve high fluoride release.
Background:Because of occupational accidents, permanent disabilities and deaths occur and economic and workday losses emerge.Objectives:The purpose of the present study was to investigate the factors responsible for occupational accidents occurred in Iran.Patients and Methods:The current study analyzed 1464 occupational accidents recorded by the Ministry of Labor and Social Affairs’ offices in Iran during 2008 - 2012. At first, general understanding of accidents was obtained using descriptive statistics. Afterwards, the chi-square test and Cramer’s V statistic (Vc) were used to determine the association between factors influencing the type of injury as occupational accident outcomes.Results:There was no significant association between marital status and time of day with the type of injury. However, activity sector, cause of accident, victim’s education, age of victim and victim’s experience were significantly associated with the type of injury.Conclusions:Successful accident prevention relies largely on knowledge about the causes of accidents. In any accident control activity, particularly in occupational accidents, correctly identifying high-risk groups and factors influencing accidents is the key to successful interventions. Results of this study can cause to increase accident awareness and enable workplace’s management to select and prioritize problem areas and safety system weakness in workplaces.
The present study aimed to assess the effect of supplementation of omega-3 and/or vitamin C on serum interleukin-6 and high sensitivity C-reactive protein concentration and depression scores among shift workers in Shahid Tondgoyan oil refinery. The study design was randomized, double-blind, placebo-controlled, parallel trial. Totally 136 shift workers with a depression score ≥10 in 21-item Beck Depression Rating Scale were randomly assigned to receive omega-3 (180 mg eicosapentaenoate acid and 120 mg docosahexaenoic acid) or/and vitamin C 250 mg or placebo twice daily (with the same taste and shape as omega-3 and vitamin C) for 60 days in four groups. Depression score, interleukin-6 and high sensitivity C-reactive protein were measured at baseline and after 60 days. This study showed that supplementation of omega-3 plus vitamin C is associated with a decrease in depression score (p<0.05). Supplementation of omega-3 without vitamin C, is associated with a reduction in depression score (p<0.0001) and high sensitivity C-reactive protein concentration (p<0.01). Therefore omega-3 supplementation showed a better effect on reducing depression score and high sensitivity C-reactive protein, but supplementation of vitamin C along with omega-3 did not have significant effect on change in C-reactive protein level compared to omega-3 alone. (Registration number: IRCT201202189056N1)
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