Background: Alopecia areata (AA) and vitiligo are associated with various psychiatric comorbidities, and the care of a child with AA or vitiligo may be associated with higher anxiety and depression than healthy children.
Aims:We aimed to identify psychiatric findings in children and adolescent groups with AA and vitiligo and to evaluate the levels of anxiety and depression in their parents.Methods: This study included 31 patients with AA and 29 patients with vitiligo, aged seven to 17 years, and their parents. Age-and gender-matched 30 controls and their parents were included. The patients and controls completed the Revised Child Anxiety and Depression Scales-Child version (RCADS-C), and their parents completed the parent version (RCADS-P). The parents also completed the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI). In addition, the stressful event history of all cases was noted.Results: Stressful event history was higher in the vitiligo group compared to the AA group, and it was higher in the AA and vitiligo groups compared to the control group. Separation anxiety, generalized anxiety, social phobia, and major depressive disorder (MDD) scores were higher in the AA group than controls according to the RCADS-C. According to the RCADS-P, panic disorder (PD), MDD, and total anxiety scores were higher in the AA group. Only the PD and MDD scores were higher in the vitiligo group than those of the controls based on the RCADS-P. Lastly, no significant difference was observed between the three groups concerning the parents' BAI and BDI scores.Conclusions: Stressful events were more common in pediatric patients with vitiligo than those with AA. Anxiety symptoms were more prevalent in patients with AA than those with vitiligo. K E Y W O R D S alopecia, psychological aspects, quality of life, vitiligo | 2233 Savaş ERDOĞaN Et al.How to cite this article: Erdoğan SS, Gür TF, Doğan B. Anxiety and depression in pediatric patients with vitiligo and alopecia areata and their parents: A cross-sectional controlled study. J
Abstract.Chitin is an important polysaccharide found as supporting material in the cell wall of mushrooms. In this study, chitin and chitosan were obtained from the cell wall of two different mushroom species using chemical method and physicochemically characterized. The dry weight chitin contents of the mushroom species were determined as 11.4% for Lactarius vellereus and 7.9% for Phyllophora ribis. Chitosan yields of the chitins isolated from L. vellereus and P. ribis were 73.1% and 75.3%, respectively. While, the maximum degradation temperatures of L. vellereus and P. ribis chitins were found to be 354°C and 275°C by thermogravimetric analysis (TGA), the maximum degradation temperature of the chitosans obtained from these chitins were recorded as 262°C and 229°C, respectively. The crystalline index values of L. vellereus and P. ribis chitins were calculated as 64% and 49%, respectively according to the X-ray diffraction analysis (XRD) results. The scanning electron microscopy (SEM) indicated that there were no nanofiber or nanopores on the surface of the chitins and chitosans obtained from these two mushroom species. The results of this study revealed that L. vellereus and P. ribis had higher chitin contents than some other insects and mushroom species recorded in the literature and these species may be used as a potential chitin sources.
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