PDE-5 inhibitors may produce EEG abnormalities. Although the exact role of PDE in altering susceptibility to seizure remains unclear, epileptic seizures may occur during treatment with PDE inhibitors.
Brusella, klinik önemi morbiditesinin ağırlığından ve pek çok farklı klinik formda ortaya çıkabilmesinden kaynaklanan bulaşıcı bir hastalıktır. Nörobruselloz; kranial sinir patolojileri, optik staz, menenjit, myelit, radikulopati, periferik nöropati tabloları görülebilir ya da klinik tablo değişik kombinasyonlarla şekillenebilir. Olgumuzun, 69 yaşında bayan hasta, şikayetleri 3 yıl önce bel ağrısı ile başlamış. Son 1 yıldır ayakta desteksiz duramamaktaydı. Kranial MRI'da bilateral periventriküler beyaz cevherde kronik iskemik değişiklikler, sağ serebellar hemisferde ansefalomalezik alan saptandı. Hastanın tanıya yönelik araştırmalarında Brusella tüp agglütinasyon 1/160 (+) olarak bulundu. Nörobruselloza yönelik tedavi sonucunda klinik düzelme gözlemlendi. Nörobruselloz, farklı klinik formlarda kendini gösterebilen bir çok durumun ayırıcı tanısında dikkate alınması gereken bir klinik tablodur.
INTRODUCTION: Environmental and personal factors may be of importance for stroke risk. We determined the stroke risk factors among the stroke patients' couples and controls. MATERIAL AND METHODS: A prospective study was conducted on 221 participants (71 stroke patients, 71 stroke patients' couples, 79 controls) aged more than 54 years. Framingham Stroke Risk Profile was used to measure the stroke risk. RESULTS: In subjects aged 54 years and older, became a couple of stroke patient were not associated with an increased risk of stroke. CONCLUSION: In this study, environmental and personal factors were an independent risk factor for stroke in stroke patients' couples and controls older than 54 years.
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