Sarcopenia is prevalent as the aging population grows. Therefore, the need for supplements for the elderly is increasing. This study aimed to investigate the efficacy and mechanism of a Panax ginseng berry extract (GBE) and soluble whey protein hydrolysate (WPH) mixture on a sarcopenia-related muscular deterioration in aged mice. Ten-month-old male C57BL/6J mice were administered three different doses of the GBE + WPH mixture for 8 weeks; 700 mg/kg, 900 mg/kg, and 1100 mg/kg. Grip strength, serum inflammatory cytokines level, and mass of muscle tissues were estimated. The deteriorating function of aging muscle was investigated via protein or gene expression. Grip strength and mass of three muscle tissues were increased significantly in a dose-dependent manner, and increased anti-inflammatory cytokine alleviated systemic inflammatory state. The mixture resolved the imbalance of muscle protein turnover through activation of the PI3K/Akt pathway and increased gene expression of the muscle regeneration-related factors, while decreasing myostatin, which interferes with muscle protein synthesis and regeneration. Furthermore, we confirmed that increased mitochondria number in muscle with the improvement of mitochondrial biogenesis. These physiological changes were similar to the effects of exercise.
Artemisia princeps Pampanini used as a medicinal herb in Asian countries has undesirable flavors. Water extracts from A. princeps Pampanini were used to quantitatively evaluate off-flavor volatiles and bioactive phenolic compounds through activated carbon (AC) processing using GC/MS and reversed-phase HPLC analyses, respectively. As the amount of AC increased, the content of individual volatiles and phenolic compounds gradually decreased. AC treatment significantly (p<0.05) decreased amounts of six off-flavor volatiles, compared to controls without AC treatment. With AC treatment, quantities of the C10 volatiles 1,8-cineol, γ-terpinene, and α-terpineol decreased by over 55%, whereas quantities of the C15 volatiles transcaryophyllene and trans-β-farnesene decreased by less than 40%. Water extracts treated with 1% (w/v) AC exhibited a non-significant (p>0.05) loss of major phenolic compounds, compared to controls. Treatment with 1% (w/v) AC effectively removes off-flavor compounds and achieves minimal loss of phenolic compounds.
In this paper, the system level EMC radiated emission test results of KoDSat(Korea Demonstration Satellite), its affects upon the Launch vehicle and H/W improving methods regarding its over exceed value of EMC specification are discussed.Regarding its over exceed value, we estimated that DAU of KoDSat generated the exceeded EMC noise source, and these test results were analyzed using the EMC2000 tool to find out how did it affect the FTS(Flight Termination Subsystem) of KSLV-1(Korea Small Launch Vehicle). To diminish the EMC noise source of UHF(430.1Mhz) band level, we redesigned the DAU power board to be applied the various schemes for EMI noise reduction such as grounding, shielding and EMI filtering, and also verified these reworks to analyze its diminishing affects in UHF band level by means of performing the DAU box level EMC test and performing the second KoDSat's system level EMC test.
Although HHP processing is getting popular in the food industry, there are limited researches focused on the inactivation kinetics of enzymes such as polyphenoloxdiase (PPO) and peroxidase (POD) under HHP. The objective of this work was to elucidate the thermal and non-thermal inactivation kinetics of PPO and POD in citrus and apple juices. The citrus and apple used in this experiment were purchased from the local market. Fruit juices were extracted using a blender and were treated by heat (at 70-80 o C for 10-30 min) and pressure (at 100-500 MPa for 10-60 min). HHP conditions used in this study were not sufficient enough to inactivate PPO and POD in both citrus and apple juices. PPO was relatively more heat and pressure stable than POD. Results of the HHP treatment could not be applied to kinetic modeling because the inactivation degree of both enzymes was almost insignificant. Through the results of the activation energy, this study suggested that the POD of citrus needed less energy than the POD of apple in order to inactivate enzymes.
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