BACKGROUND Polymorphic Light Eruption (PMLE) is the most common, recurrent idiopathic acquired photodermatosis with female preponderance. (1) Polymorphic light eruption has been found to be associated with thyroid function abnormalities. Aim-To study the clinico-epidemiological profile of polymorphic light eruptions and its association with thyroid function abnormalities. MATERIALS AND METHODS A prospective observational study was conducted for a period of one year from April 2017 to October 2017 in 50 patients presenting to the Outpatient Department with polymorphic light eruptions. Thyroid Stimulating Hormone (TSH), Free Triiodothyronine (FT3) and Free Tetraiodothyronine (FT4) were estimated in these patients. Inclusion criterion was patients clinically diagnosed as cases of polymorphic light eruptions. Exclusion criteria were pregnancy, lupus erythematosus, inflammatory photodermatoses, use of drugs causing photosensitivity, specific treatment of polymorphic light eruption in last 3 months. RESULTS The study showed a female preponderance (68%). The average age at presentation was 30-35 yrs. Thyroid Function Tests (TFT) showed abnormality in 40% of cases. CONCLUSION This study showed that hypothyroidism has significant association with PMLE. (2) Cases of polymorphic light eruptions should be examined clinically for thyroid disorder and also tested for TFT and thyroid autoantibodies to find any association and prevent serious consequences.
BACKGROUND Leprosy is a major public health problem in developing countries. India dominates the global picture with 60% of the world's leprosy cases. This study was done to bring about the current trends in the clinicoepidemiological profile of leprosy in a te rtiary care center. The aim of this study was to evaluate the epidemiological and clinical profile of leprosy patients in a tertiary care center. MATERIALS AND METHODS This is a descriptive study of all patients who attended Urban Leprosy Clinic (ULC) in the department of Dermato-Venereology during the period from January 2014-2017. Leprosy patients seen during this period were registered at the ULC and the records were maintained by a health inspector posted at the department, under the supervision and guidance of the consultants in the department. Clinical spectrum of the patient was determined obtaining detailed clinical history and meticulous clinical examination followed by slit skin smear examination and histopathological evaluation. All the patients were treated with paucibacillary and multibacillary drug therapy according to their disease spectrum. RESULTS A total of 214 patients attended the Urban Leprosy Clinic during the year January 2015-December 2017 in our hospital. CONCLUSION Notable thing in our study is high new case detection rate despite the reduction in prevalence rate. Lack of awareness about the disease in the community might be the cause for the delay in reporting and hence a late diagnosis resulting in majority of patients fall under multibacillary spectrum.
INTRODUCTION: This study investigated the prevalence of smoking among health care and non-health care undergraduate students in Penang. Further, the knowledge, awareness and attitude levels of the respondents were also discerned. Besides, the existence of any significant difference between the knowledge, awareness and attitude levels of the two groups was also investigated. MATERIALS AND METHODOLOGY: The population comprised the undergraduate students of Penang. Out of this population, a sample of 162 respondents were randomly selected. Survey questionnaires were given to the respondents to ascertain their prevalence of smoking and their knowledge, awareness and attitude towards smoking. Data was collected and both descriptive and inferential analysis were carried out using SPSS. RESULTS: There were proportionately less smokers among the healthcare respondents compared to the non-healthcare respondents. Additionally, it was also found that there existed a significant difference between the two groups in terms of the score for knowledge, awareness and attitude towards smoking (t=6.19, p < 0.05). CONCLUSION: Thus health care students had a lower prevalence of smoking and had greater knowledge, awareness and attitude of the dangers of smoking and were possibly aided by their greater knowledge of the health sciences.
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