Objectives:
To investigate the intercourse between the platelet/lymphocyte (P/L) and neutrophil/lymphocyte ratio (N/L), and vitamin D (Vit-D) levels in low bone mineral density (BMD) of women.
Methods:
Two hundred fifty-two postmenopausal female outpatients who were admitted to the obstetrics and gynecology and physical therapy clinics between July 2016 and December 2017 were retrospectively analyzed. The patients were grouped in relation to their T-score (normal [n=92], osteopenia [n=112], and PMO [n=48]). The serum levels of P/L, N/L, Vit-D, BMD and complete blood count of the patients were retrospectively examined.
Results:
The median P/L was significantly higher and Vit-D levels were significantly lower in the PMO group (130.75 [52.89-385] versus 123.05 [54-232.5],
p
=0.02 and 15.4 [4-34] versus 20.1 [4-47],
p
=0.003). While BMD and P/L were negatively correlated, a positive correlation between BMD and Vit-D was found. Vitamin D levels were negatively correlated with P/L (
p
<0.001) and N/L (
p
=0.04). Older age (≥65 years), Vit-D deficiency and P/L values >125.06 were found as independent prognostic factors for PMO in regression analysis.
Conclusion:
Higher P/L seems to be a quite simple marker to help predict postmenopausal PMO. As seen in our study, having low levels of Vit-D is crucial for PMO.
Üriner sistem infeksiyonu gebelikte sık görülen bir sağlık sorunudur. Ancak, gebelikte güvenle kullanılabilen antibiyotikler fetal toksisite riski nedeniyle kısıtlıdır. Bu çalışmada gebe kadınların idrar kültürlerinden izole edilen patojenlerin antimikrobiyal direnç profillerinin belirlenmesi ve ampirik tedavide tercih edilebilecek antibiyotiklerin tespiti amaçlanmıştır. Ocak 2015-Ocak 2016 tarihleri arasında Karabük Eğitim ve Araştırma Hastanesi'ne başvuran gebelerin idrar örneklerinden izole edilen bakterilerin identifikasyonu ve antibiyotik duyarlılıkları BD-Phoenix (Becton-Dickinson, USA) tam otomatize sistem ile, genişlemiş spektrumlu beta-laktamaz varlığı (GSBL) ise kombine disk difüzyon yöntemi ile araştırılmıştır. Sonuçlar retrospektif olarak incelenmiştir.
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