Here in this paper our main motive is to improve the In this paper, we have introduced RSA cryptosystem and its efficiency of RSA cryptosystem. The first section of the improvements. There are many cases when there is the need to paper describes brief review of RSA Cryptosystem. In enhance the decryption/signature generation speed at the cost of Second section various methods for the improvement encryption/signature verification speed, e.g., in banks, signature over standard RSA is reviewed. Then our proposed generation can be in huge amount in a single day as compared scheme is shown with the result analysis. The paper is to only one signature verification in the complete day at then lu in th t setion.receiver side. So here in this paper the main stress is on the then concluded in the last section.improvement of decryption/signature generation cost. Many 2. RSA methods are discussed to improve the same, e.g., Batch RSA, In cryptography, RSA [3] is a public key algorithm. MultiPrime RSA, MultiPower RSA, Rebalanced RSA, RPrimeThe algorithm was publicly described in 1977 by Ron RSA. The proposed approach to improve decryption/signature Rivest, Adi Shamir and Leonard Adleman at MIT. It is generation speed is given in the paper. We have tried the the first algorithm known to be suitable for encryption as improvement by the combination of MultiPower RSA and well as signing, and one of the first great advances in Rebalanced RSA. Theoretically, the proposed scheme (for key well as cryptgrand RSA is grely ad in length 2048 bits moduli) is about 14 times faster than that given public key cryptography. RSA is widely used in by RSA with CRT and about 56 times faster than the standard electronic commerce protocols. Given sufficiently long RSA. Tabular and graphical comparison with other variants of keys and the use of up-to-date implementations; RSA is RSA is also shown in the paper.believed to be totally secure. The concept behind public-

A Mobile Ad hoc Network is a collection of mobile nodes that dynamically forms networks temporarily

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Multiple inputs multiple output orthogonal frequency division multiplexing (MIMO-OFDM) is an attractive transmission technique for high bit-rate communication systems. MIMO-OFDM has become apromising candidate for high performance 4G broadband wireless communications. One main disadvantage of OFDM is the high peak-to-average power ratio (PAPR) of the transmitter's output signal. Selected-Mapping (SLM) scheme which does not require the transmission of side information and can reduce the peak to average power ratio (PAPR) in turbo coded orthogonal frequency division multiplexing (OFDM) system is proposed. Simulation results show that the system can achieve significant reduction in PAPR and satisfactory bit error rate performance over AWGN channels.

BACE-1 and GSK-3β are potential therapeutic drug targets for Alzheimer's disease. Recently, both the targets received attention for designing dual inhibitors for Alzheimer's disease. Until now, only two-scaffold triazinone and curcumin have been reported as BACE-1 and GSK-3β dual inhibitors. Docking, molecular dynamics, clustering, binding energy, and network analysis of triazinone derivatives with BACE-1 and GSK-3β was performed to get molecular insight into the first reported dual inhibitor. Further, we designed and evaluated a naphthofuran series for its ability to inhibit BACE-1 and GSK-3β with the computational approaches. Docking study of naphthofuran series showed a good binding affinity towards both the targets. Molecular dynamics, binding energy, and network analysis were performed to compare their binding with the targets and amino acids responsible for binding. Naphthofuran series derivatives showed good interaction within the active site residues of both of the targets. Hydrogen bond occupancy and binding energy suggested strong binding with the targets. Dual-inhibitor binding was mostly governed by the hydrophobic interactions for both of the targets. Per residue energy decomposition and network analysis identified the key residues involved in the binding and inhibiting BACE-1 and GSK-3β. The results indicated that naphthofuran series derivative 11 may be a promising first-in-class dual inhibitor against BACE-1 and GSK-3β. This naphthofuran series may be further explored to design better dual inhibitors. Graphical abstract Naphthofuran derivative as a dual inhibitor for BACE-1 and GSK-3β.

The wireless communication systems has gone from different generations from SISO systems to MIMO systems. Bandwidth is one important constraint in wireless communication. In wireless communication, high data transmission rates are essential for the services like tripple play i.e. data, voice and video. At user end the capacity determines the quality of the communication systems. This paper aims to compare the different RF wireless communication systems like SISO, MISO, SIMO and MIMO systems on the capacity basis and explaining the concept as today, the wireless communication has evolved from 2G, 3G to 4G and the companies are fighting to create networks with more and more capacity so that data rates can be increased and customers can be benefitted more. The ultimate goal of wireless communication systems is to create a global personal and multimedia communication without any capacity issues.

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Abstract-Investigations in hydrologic sciences are bounded because most of existing water surveillance methods are manual. Such systems are incapable to gather information at spatial and temporal level due to location constraints. In this paper, we present a new communication architecture for Underwater Wireless Sensor Network (UWSN) based on acoustic communication. However, unique challenges offered by underwater environment are main hindrance in deployment of UWSN in real life applications. So, we discuss various communication methodologies to figure out which one suits best to the requirements of UWSN. Our simulation results illustrate change in data transmission rate, energy consumption and transmission time w.r.t transmission range and number of nodes in network. Results prove that multi-hop communication offer high transmission rate, large bandwidth. Moreover, multi-hop communication is much more energy and time efficient than direct communication.