There have been limited reports describing reflectance confocal microscopy (RCM) features of Bowen’s disease (BD). Herein, we describe the RCM features of a pigmented BD with atypical dermoscopic features, mimicking a melanoma. This case highlights the importance of RCM in a challenging BD.

There have been limited cases of pedunculated basal cell carcinoma (BCC) reported in the literature. The dermoscopic features were described in only one of them. However, not one of them described the confocal microscopy features. In this report we presented a case of pedunculated basal cell carcinoma (BCC) with dermoscopic and reflectance confocal microscopy features.

The mean (±SD) age was 39.1 ± 12.6 years. Ophthalmological examination was abnormal in 51 patients (71.8%) and normal in 20 patients (28.2%). Ocular complaint was recorded in 33.8% of patients. The primary lesion in the anterior segment was conjunctivitis (31%). The most common lesions of the posterior segment were cytomegalovirus retinitis (7.1%) and HIV retinopathy (5.7%). The mean CD4 count in our study was 206.8 ± 229.8 cells/mm 3 . 71.4% of patients with ocular manifestations had a CD4 count less than 200 cells/mm 3 . Ocular manifestations and CD4 cells count, no significant statistical relationship was found (P = 1,0000). Conclusion With access to antiretroviral therapy, ocular manifestations of HIV/AIDS are increasingly less frequent. Ocular manifestations were not related to the CD4 cells count in this study.This study, the first in our area, will guide the ophthalmologist and let him play its role mainly in the diagnosis and care of patients.

I n t h i s study, the enzymatic oxidation o f acetaldehyde, one o f the s u b s t r a t e s of santhine oxidase, has been studied bya microcalorimetric method. A f l o w microcalorimeter i s used t o measure the h e a t changes during the reaction. The c a t a l y t i c determination of xanthine oxidase between the concentrations 0.2~10-1 and 2.4~10-l m g / m l (0.8~lO'~ -9.6fioe3 U / d ) has been achieved keeping acetaldehyde concentration constant at 4.0~10-~ I and the catalymetric determination of acetaldehyde between 0.8~lO'~ and 208fiO-~ M i s accomplished at a fixed concentration of enzyme.

Objective: Adipose tissue is the most abundant source of accessible stroma. The stromal cells proliferate and differentiate to mature adipocytes by different hormonal stimulus. Insulin was known to be associated with fat cell proliferation. The aim of this study was to investigate the varying concentrations of insulin effect on the proliferation of human subcutaneous and visceral adipose tissue cultures. Subcutaneous and omental adipose tissue was obtained from a 34 years old female donor aged with a body mass index (BMI) of 34.1 kg/m 2 . Sromal vascular cells were isolated and cultured using modified procedures described by Entenmann and Hauner. For the proliferation assay, stromal-vascular cells from subcutaneous and omental adipose tissue cultures were fed with proliferation media containing 100 nM, 200 nM, 400 nM insulin, for 3 days. Cell numbers and sizes of proliferating cultures of human omental adipose tissue cultures increased more than human subcutaneous adipose tissue culture at the level of 100 nM and 200 nM insulin concentrations. All cells of adipose cultures died at the 400 nM insulin concentration. High insulin levels (400 nM) have a toxic effect on adipose cells. Insulin effects the number and size of omental adipose cells more than the subcutaneos adipose cells.