We present a modular semantic account of Bayesian inference algorithms for probabilistic programming languages, as used in data science and machine learning. Sophisticated inference algorithms are often explained in terms of composition of smaller parts. However, neither their theoretical justification nor their implementation reflects this modularity. We show how to conceptualise and analyse such inference algorithms as manipulating intermediate representations of probabilistic programs using higher-order functions and inductive types, and their denotational semantics. Semantic accounts of continuous distributions use measurable spaces. However, our use of higher-order functions presents a substantial technical difficulty: it is impossible to define a measurable space structure over the collection of measurable functions between arbitrary measurable spaces that is compatible with standard operations on those functions, such as function application. We overcome this difficulty using quasi-Borel spaces, a recently proposed mathematical structure that supports both function spaces and continuous distributions. We define a class of semantic structures for representing probabilistic programs, and semantic validity criteria for transformations of these representations in terms of distribution preservation. We develop a collection of building blocks for composing representations. We use these building blocks to validate common inference algorithms such as Sequential Monte Carlo and Markov Chain Monte Carlo. To emphasize the connection between the semantic manipulation and its traditional measure theoretic origins, we use Kock's synthetic measure theory. We demonstrate its usefulness by proving a quasi-Borel counterpart to the Metropolis-Hastings-Green theorem

We present the results from four stellar occultations by (486958) Arrokoth, the flyby target of the New Horizons extended mission. Three of the four efforts led to positive detections of the body, and all constrained the presence of rings and other debris, finding none. Twenty-five mobile stations were deployed for 2017 June 3 and augmented by fixed telescopes. There were no positive detections from this effort. The event on 2017 July 10 was observed by SOFIA with one very short chord. Twenty-four deployed stations on 2017 July 17 resulted in five chords that clearly showed a complicated shape consistent with a contact binary with rough dimensions of 20 by 30 km for the overall outline. A visible albedo of 10% was derived from these data. Twenty-two systems were deployed for the fourth event on 2018 Aug 4 and resulted in two chords. The combination of the occultation data and the flyby results provides a significant refinement of the rotation period, now estimated to be 15.9380 ± 0.0005 hours. The occultation data also provided high-precision astrometric constraints on the position of the object that were crucial for supporting the navigation for the New Horizons flyby. This work demonstrates an effective method for obtaining detailed size and shape information and probing for rings and dust on distant Kuiper Belt objects as well as being an important source of positional data that can aid in spacecraft navigation that is particularly useful for small and distant bodies.

Abstract-We present a denotational account of dynamic allocation of potentially cyclic memory cells using a monad on a functor category. We identify the collection of heaps as an object in a different functor category equipped with a monad for adding hiding/encapsulation capabilities to the heaps. We derive a monad for full ground references supporting effect masking by applying a state monad transformer to the encapsulation monad. To evaluate the monad, we present a denotational semantics for a call-by-value calculus with full ground references, and validate associated code transformations.

I would like to thank my supervisor, Martin Hyland, for his guidance, insight, and encouragement, as well as for patiently reading and critiquing many drafts of this work. Thanks go to Tamara von Glehn for having written her own thesis (without which this one could not have been written), for many helpful conversations, and for giving many useful comments on several drafts. I am grateful to the examiners, Marcelo Fiore and Nicola Gambino, for their careful reading and thoughtful suggestions. It has been a privilege to be part of the category theory group in Cambridge, and I am grateful to the many official and honorary members of our group for their support. My thanks to everyone else who has kept me going, including friends in Cambridge and elsewhere, and especially my parents, Ian and Jacqui, and my sister, Katharine.