[ 5 b] GMA based polyHIPEs have been prepared for the separation of proteins. [ 8 ] A low HLB number (0.5) surfactant (triblock

Highly porous polymeric materials are prepared by thiol-ene and thiol-yne mediated network formation using high internal phase emulsion templates. The efficiency of network formation is between 80 and 90% for all materials while the thiol-yne materials display enhanced strength and toughness due to their higher degree of crosslinking.

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Abstract. Electrospinning is considered a relative simple and versatile technique to form high porosity porous scaffolds with micron to nanoscale fibers for biomedical applications. Here, electrospinning of unsaturated aliphatic polyglobalide (PGl) into well-defined fibers with an average diameter of 9 µm is demonstrated. Addition of a dithiol crosslinker and a photoinitiator to the polymer solution enabled the UV-triggered intra-crosslinking of the fibers during the spinning process. The in-situ crosslinking of the fibers resulted in amorphous material able to swell up to 14% in tetrahydrofyrane (THF) without losing the fiber morphology. Seeding Mesenchymal Stem Cells (MSCs) onto both crosslinked and non-crosslinked PGl fibers proved their compatibility with MSCs and suitability as scaffolds for cell growth and proliferation of MSCs. Moreover, the ability to directly load crosslinked PGl with hydrophobic molecules by soaking the fiber mesh in solution is shown with Rhodamine B and Indomethacin, a hydrophobic anti-inflammatory drug. This marks an advantage over conventional aliphatic polyesters and opens opportunities for the design of drug loaded polyester scaffolds for biomedical applications or tissue engineering.