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Context and Aim: Formocresol has been used as the material of choice (gold standard) for pulpotomy procedures because of the ease of use but was discouraged due to its potential immune sensitization and mutagenic effects. Laser irradiation was first applied for pulpotomy procedure in the year 1985. Recently, diode lasers have been used for pulpotomy in primary teeth and have shown clinical success rates comparable to formocresol. The present in vivo study was carried out to compare the clinical and radiographic success rates of mineral trioxide aggregate (MTA) pulpotomy and diode laser-assisted pulpotomy in human primary molars. Materials and Methods: The present study was a randomized clinical trial in design wherein 40 primary teeth requiring pulpotomy treatment which met the selection criteria (clinical and radiographic) were divided into two groups, Group 1 ( n = 20) wherein the pulpotomy was performed with MTA alone and Group 2 ( n = 20) wherein laser-assisted pulpotomy was performed with MTA (L-MTA). The patients were recalled after 3, 6, and 9 months, respectively and evaluated clinically and radiographically. Statistical Analysis Used: The data were analyzed using the Statistical Package for the Social Sciences (SPSS) Version 22 (IBM corporation, Washington DC, United States). Descriptive statistics were used to analyze the data while the Pearson's correlation coefficient test was used to analyze the statistical correlation between the overall success rates observed in the clinical and radiographic findings of both the groups. P < 0.05 was considered statistically significant. Results: The clinical success rate in the MTA group was 90%, 84.21%, and 88.23% at 3, 6, and 9 months, respectively, with no clinical signs or, symptoms reported at the said follow-up visits while the radiographic success rate was found to be 85%, 84.21%, and 82.3%, respectively. On the contrary, the clinical success rate in the L-MTA group was found to be 95%, 94.74%, and 94.44% at 3, 6, and 9, months, respectively with the radiographic success rate reported being 90%, 89.47%, and 88.89%, respectively. Conclusion: The combination of diode laser and MTA yielded better clinical and radiographic success rates over the pulpotomy procedures done with the help of MTA alone, thereby, concluding that lasers may be considered as adjuvant alternatives for vital pulp therapy on human primary teeth.

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Photobiomodulation (PBM), also commonly referred to as low-level laser therapy (LLLT), uses light energy to elicit biological responses from the cell and normalize cell function. 40 persons with periapical lesions were selected and were assigned randomly into two groups.Group I - Conventional root canal therapy and low-level laser therapy. Group II – Conventional root canal therapy Root canal therapy was completed, and radiographs were obtained and assessed 3, 6, and 9 months postoperative. VAS pain scale was assessed postoperatively on 0, 7th, and 14th days respectively. An independent t-test was used for the evaluation of the data. No significant difference was noted for postoperative pain and PAI scale between both groups Significant difference was noted in the reduction of the periapical lesions for 3 and 9 months follow up, but was not significant for 6 months. The healing was better in Group I which received Low-level laser therapy with the conventional root canal treatment. Low-level laser therapy can be the newer additional treatment modality that can be applied to the periapical lesion for its faster healing.

Objective: Even when endodontic procedures are performed with the utmost care, reinfection can occur. One possible explanation is that contaminated gutta-percha cones were used in the root canals. The study's goal is to assess the antimicrobial activity and efficacy of Neem, Turmeric, and Calotropis Procera in disinfecting gutta percha cones prior to obturation. Materials and Methods: 80 Gutta percha (GP) cones were contaminated with 0.5ml Ferlands standard Enterococcus Faecalis for 10 minutes.20 cones each were treated up to 5 minutes in their prepared neem, turmeric, calotropis and sodium hypochlorite solutions. Then, they placed in BHI broth and vertex is done for 1 minute. One loopful of broth was stroked on 20 blood agar plates of 5 each neem, turmeric, calotropis and sodium hypochlorite. The plates were then incubated for 24 hours aerobically at 37°C and the colony forming units were counted with a digital colony counter. Results: Mean colony forming units were compared in all the groups and there was a statistically significant difference present among the groups (p<0.01). Sodium Hypochlorite (NaOCL)as control group showed average of 5 colony forming units(CFU). Turmeric had the least average of 55 CFU and was the most effective of the experimental groups. Neem and Calotropis had the higher average of 130 CFU and 200 CFU respectively, making it the least effective of the solutions tested. Conclusion : All of the herbal solutions tested positive for disinfection of GP points. When compared to Neem and Calotropis, Turmeric was the most effective and has superior antibacterial activity.

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