Henna leaves are often used as traditional medicine, including as an antibacterial. Henna leaves contain several active components including phenols and flavonoids which act as antibacterial. The purpose of this study was to determine antibacterial activity of ethanol extract of henna leaves (Lowsonia inermis L.) against Staphyloccocus aureus. This research was conducted using descriptive method. In this study, ethanol extract of henna leaf was made by maceration method. Ethanol extract of henna leaves was tested against Staphylococcus aureus on Nutrient Agar (NA) medium using well diffusion method with 3 extract concentrations, namely 40%, 50% and 90%, tetracycline as positive control and aquadest as negative control with 3 repetitions each. The results of this study showed that inhibition zone diameter of henna leaves extract at a concentration of 40% was 21.29 mm, at a concentration of 50% was 23.1 mm and at a concentration of 90% was 24.4 mm, positive control was 27.93 mm and negative control did not show inhibition zone. The inhibition zone for all concentrations belongs to strong inhibition category.
Sponge-associated actinobacteria may diverse and have potency to produce bioactive compounds. Diversity and antimicrobial activity of indigenous sponge-associated actinobacteria isolated from the marine ecosystem in Indonesia have not much been explored. This work aimed to assess morphological and antibacterial activity of sponge-associated actinobacteria. The morphological characteristics were examined based on their color of aerial and substrate mycelia, and pigmentation, while antibacterial activities were assayed using the antagonist technique. The selected actinobacterial isolate was identified using 16S rRNA gene. Various sponge-associated actinobacteria were successfully isolated from Hyrtios sp., Callyspongia sp., and Neofibularia sp. sponges. A total of 62 actinobacterial isolates were obtained, and each isolate showed a variety of morphological characters, which could be seen in aerial mass color, substrate mass color, and pigmentation. Actinobacterial isolates were tested against human pathogenic bacteria, i.e. Staphylococcus aureus and Methicillin-Resistant S. aureus, representing Gram-positive, and Escherichia coli EPEC K1-1 and Shigella dysenteriae, representing Gram-negative. Most of actinobacterial isolates had antimicrobial activities at least against one of pathogenic bacteria. High activity was shown by NOHa.2, isolated from Neofibularia, and HRHa.5 isolated from Hyrtios. The NOHa.2 showed the highest antimicrobial activity against S. dysenteriae, meanwhile, HRHa.5 showed antimicrobial activity against 3 of 4 tested bacterial pathogens. These data showed diversity of sponge-asccociated actinobacteria from marine ecosystem in Indonesia, and several of them have potency as source of antibacterial compounds
Purple sweet potato leaf (Ipomoea batatas L.) is one of the plants that has begun to be used as a traditional or herbal medicine. This study aims to determine the content of secondary metabolites from purple sweet potato leaves. This research was conducted at the Chemistry Laboratory, Faculty of Tarbiyah, State Islamic University of Ar-Raniry Banda Aceh with laboratory testing methods. Purple sweet potato leaves were extracted by maceration using 5 L 96% ethanol for 5 days and evaporated in a vacuum rotary evaporator to form a thick extract. Furthermore, phytochemical screening tests were carried out. The test results stated that purple sweet potato leaf extract contains Alkaloids (+++), Flavonoids (+), Tannins (+), Saponins (+), Terpenoids (+), and Steroids (+).
Masyarakat khususnya ibu-ibu di Desa Beurangong Aceh Besar biasa menggunakan obat-obatan secara empiris. Hal tersebut dapat dilihat dari sebagian pekarangan rumah mereka ditanami dengan tanaman toga. Akan tetapi, masyarakat lain belum semuanya mengetahui jenis-jenis tanaman toga dan manfaat yang diberikan tanaman toga. Pengabdian masyarakat ini dilaksanakan oleh dosen-dosen Akademi Farmasi YPPM Mandiri sebagai wujud tri dharma perguruan tinggi. Kegiatan ini dihadiri oleh ibu-ibu di Desa Beurangong Kecamatan Lam Ateuk Kabupaten Aceh Besar. Metode pelaksanaan kegiatan ini adalah dengan memberikan penyuluhan secara oral dan melakukan diskusi berupa tanya jawab. Hasil kegiatan ini adalah sebagian masyarakat telah terbiasa menanam tanaman toga di pekarangan rumah. Ada sekitar18 jenis tanaman yang banyak di tanam di pekaranga rumah masyarakat.
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