No abstract

No abstract

As aspirin is now widely used for preventing recurrence of cardiovascular and cerebrovascular disorders, many men selected for transurethral resection of the prostate (TURP) are aspirin users. The previous indication for aspirin as a preoperatively administered antithrombotic agent is no longer common. In this study we investigated the blood loss in long-term aspirin users (250 mg/day) undergoing TURP. The mean blood loss in the 40 aspirin users was 358 (range 50-1550) ml, and in a control group of 42 men it was 478 (40-2400) ml. When mean blood loss was correlated to operating time and prostatic weight, the intergroup difference was not significant. In the late postoperative period two aspirin-treated men had bleeding with tamponade of the urinary bladder requiring emptying in the operating room. As blood loss was not enhanced by aspirin use, avoidance of aspirin before TURP appears to be unnecessary.

Icodextrin treatment resulted in a decreasing trend in adhesiolysis time. The use of 4% ID solution in peritonitis patients seemed to be safe. Because of larger than expected variations in adhesiolysis times, this pilot study was underpowered to meet the study end-point and further statistical modelling estimated that significance cannot be reached within a reasonable time scale. Other models should be used to evaluate the efficacy of anti-adhesive agents.