<p class="abstract"><strong>Background:</strong> Ano-genital wart, an infection of the anal and genital mucosa with their adjoining area is caused by human papilloma virus. Genital warts pose a bigger challenge, because of the lack of cell mediated immunity and its propensity to relapse and the reluctance of patients to consult a physician. The main aim of our study is to determine whether autoinoculation is effective in treatment of ano-genital warts.</p><p class="abstract"><strong>Methods:</strong> 25 cases of anogenital warts of either sex, who attended RTI/STI clinic in Chengalpattu Medical College from September 2017 to September 2018. The study design was prospective. A detailed history taking, thorough clinical examination and appropriate relevant investigations were done for all the patients who fulfilled the inclusion and exclusion criteria. Autoinoculation was done for those patients. They were assessed periodically for clinical outcome.<strong></strong></p><p class="abstract"><strong>Results:</strong> A sample size of 25 patients (20 men and 5 women) was included in the study. After 3 months of therapy 8 (32%) patients recovered completely and more than 75% improvement occurred in another 7 (28%) patients. At 6 months 15 (60%) patients showed complete resolution. No significant complication was documented.</p><p class="abstract"><strong>Conclusions:</strong> Autoinoculation is a single time minimal invasive procedure effective in management of anogenital wart. It also reduces the recurrence of lesions.</p>
<p class="abstract"><strong>Background:</strong> Atrophic acne scars are one of the sequalae that follows acne vulgaris. These scars are big cosmetic concern presenting with varied morphology like ice-pick, rolling and boxcar scars and it needs multimodal approach to treat effectively rather than a single modality. Our main aim is to study the efficacy of combination therapy using subcision, micro-needling and trichloro acetic acid chemical reconstruction of skin scars (TCA CROSS) in a sequential manner for the management of atrophic acne scars.</p><p class="abstract"><strong>Methods:</strong> Total 30 patients of either sex with grade 2, 3, and 4 atrophic acne scars were graded using Goodman and Baron qualitative grading and were enrolled in the study. After single sitting of subcision, micro-needling and 50% TCA CROSS were performed alternatively at 3 weeks interval for a total of 3 sessions of each. Grading of acne scars were done by taking photographs at pre-treatment, post treatment, 1st and 3rd month after last treatment session.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 14 patients with grade 4 acne scars, 9 (64.3%) patients improved to grade 2 and 5 (35.7%) patients improved to Grade 3. Out of 10 patients with Grade 3 scars, 6 (60%) patients improved to grade 1, and 4 (40%) patients were improved to grade 2 at the end of study. All 5 patients with Grade 2 scars showed significant improvement from baseline.</p><p class="abstract"><strong>Conclusions:</strong> Subcision, micro-needling and TCA CROSS, if they are combined and adequately done in proper manner will have excellent response in all types of atrophic acne scars.</p>
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