Experimental investigation on discharge coefficient, Cd, for high viscosity fluid through nozzles was carried out. The viscosity of the fluid used for the test ranged from 350 to 1500 mPa s. The length-to-diameter ratio of the nozzle, / and the ratio of nozzle diameter to pipe diameter ratios were used to investigate the influence of geometry on Cd. Results show a significant dependence of Cd on Re, l/d and β ratio. An empirical correlation on the discharge coefficient was developed based on the data from this study which was also compared with data from other published studies. This correlation, with an R-squared value of 0.9541, was valid for nozzle sizes 10-20 mm and for Re between 1 and 2000. Cd values obtained from experimental data, and those from the empirical correlation were compared, and a mean standard deviation of 0.0231 was obtained.

<b><i>Background:</i></b> Unlike what obtains in childhood-onset type 1 diabetes, there remains a paucity of data on adult-onset type 1 diabetes in Nigeria. Hence, the current study aimed to determine the general characteristics of adult-onset type 1 diabetes among subjects (aged ≥18 years) presenting at the University of Uyo Teaching Hospital (UUTH) in Akwa Ibom State, South-south Nigeria. <b><i>Methods:</i></b> A 5-year (2014–2018) retrospective records review of subjects with type 1 diabetes was undertaken, using hospital medical records retrieved from the Department of Health Information Management of UUTH. Diagnosed adult cases of type 1 diabetes were meticulously identified and the relevant data at the point of initial diagnosis were acquired on a specially designed data acquisition template. <b><i>Results:</i></b> A total of 47,357 medical cases were identified of which 362 adults were diagnosed with type I diabetes (mean age 33.12 ± 4.40, range 20–51 years) and the females (<i>n</i> = 204; 56.4%) predominated among those diagnosed. The overall, male gender, and female gender prevalence was 7.4/1,000 (95% confidence interval [CI]: 6.89–7.98), 3.3/1,000 (95% CI: 2.52–4.08), and 4.3/1,000 (95% CI: 3.61–4.99), respectively. The females exhibited the highest trough, peak, annual, and overall prevalence during the study period. The female gender (OR: 2.334; 95% CI: 1.407–3.478; <i>p</i> = 0.010), age ≤30 years (OR: 1.976; 95% CI: 0.875–3.211; <i>p</i> &#x3c; 0.001), urban-dwelling (OR: 3.243; 95% CI: 2.3407.780; &#x3c;0.001), diabetes family history (OR: 1.365; 95% CI: 0.678–2.010; <i>p</i> = 0.033), and the rainy season (OR: 1.129; 95% CI: 0.401–1.910; <i>p</i> &#x3c; 0.001) were independent predictors among the overall adult type 1 diabetics. On gender-segregated analyses, age ≤30 years, urban-dwelling, diabetes family history, and the rainy season remained independent predictors among the male and female adult type 1 diabetics (<i>p</i> &#x3c; 0.05). <b><i>Conclusion:</i></b> The study demonstrated a high burden of type 1 diabetes among adult residents of Uyo, Akwa Ibom State, South-South Nigeria. The predictors of adult type 1 diabetes, identified in the present study, are valuable epidemiologic evidence for the design of type 1 diabetes-targeted preventive programs by various concerned stakeholders.

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Over the years, traditional medicine has been used to treat various degrees and forms of ailment with significant positive therapeutic outcomes. We designed this research to ascertain the use of Lantana camara as a potent factor in improving gastric ulcer caused by the administration of aspirin in Wistar rats. 250mg/kg of the extract was used to evaluate the anti-ulcer capacity of the plant extract. The omeprazole was used as a standard drug (20mg/kg). It was found that the Gastric mucosa was significantly improved after the administration of 250mg/kg of the extract after aspirin-induced ulcer.  The present study justifies the traditional usage of this plant to treat the gastric ulcer.