Lipid/Lipoprotein Abnormalities Among Adult Type 1 Diabetics in Nigeria

Lipid profiles of Nigerians living with type 2 diabetes mellitus: A systematic review and meta-analysis

“…[49] Similarly, in a meta-analysis done among Ethiopians living with T2D, the prevalence of low HDL-C was reported as 44.36%, which is similar to the findings of this present meta-analysis. [50] Insulin resistance enhances the increased production of TRLs which exchange triglyceride Isezuo et al [19] 2003 Cross-sectional 40 25% NW Isezuo and Ezunu [20] 2005 Cross-sectional 254 72.4% NW Idogun et al [21] 2007 Cross-sectional 52 30% SS Okafor et al [22] 2008 Cross-sectional 192 89% SW Unadike et al [23] 2008 Cross-sectional 32 68.7% SS Ogbera et al [24] 2009 Cross-sectional 600 89% SW Kayode et al [25] 2010 Cross-sectional 113 50.4% SW Edo and Adediran [26] 2011 Cross-sectional 52 32.7% SS Jisieike-Onuigbo et al [27] 2011 Cross-sectional 108 90.7% SE Okafor et al [22] 2012 Cross-sectional 233 97.1 SE Oyelade et al [28] 2013 Cross-sectional 219 58.5% SW Edo et al [29] 2014 Retrospective 63 30.2% SS Ogedengbe and Ezeani [30] 2014 Cross-sectional 106 50.8% SE Edo and Edo [31] 2016 Retrospective 130 29.2% SS Enikuomehin et al [32] 2016 Cross-sectional 300 50.4% SW Fasanmade et al [33] 2016 Cross-sectional 218 80.7% SW Young and Onyenekwe [34] 2016 Cross-sectional 51 82.4% SE Omotoye and Fadupin [35] 2017 Cross-sectional 50 70% SW Engwa et al [36] 2018 Cross-sectional 72 40.8% SE Bello-Ovosi et al [37] 2019 Cross-sectional 322 69.3% NW Jaja and Yarhere [38] 2019 Cross-sectional 22 86.4% SS Amadi et al [39] 2020 Retrospective 346 46.8% SS NW: North-west, SS: South-south, SW: South-west, SE: South-east with cholesterol on HDL-C, making the HDL-C more susceptible to increased clearance from the bloodstream. [51] This invariably leads to low HDL-C.…”

“…The prevalence of dyslipidemia among Nigerians with T2D is very high. The most commone abnormalities are Isezuo et al [19] 40 0 10.5 28.1 12.3 Idogun et al [21] 52 92.3 30.8 100 92.3 Okafor et al [22] 192 58.9 25 88 55.2 Ogbera et al [24] 600 74 53 13 42 Kayode et al [25] 113 0 10.5 28.1 12.3 Edo and Adediran [26] 52 9.6 19.2 32.7 26.9 Jisieike-Onuigbo et al [27] 108 44.4 56.5 62 53.7 Oyelade et al [28] 219 23.7 16 44.3 12.3 Edo et al [29] 63 30.2 7.9 25.4 17.5 Ogedengbe and Ezeani [30] 106 41.1 27 50.8 34.7 Edo and Edo [31] 130 26.9 9.2 29.2 13.1 Enikuomehin et al [32] 187 38.3 24.7 28.3 28.3 Omotoye and Fadupin [35] 50 34 86.4 72 36 Engwa et al [36] 72 27.7 40.8 NA 39.4 Jaja and Yarhere [38] 22 34 86.4 36.4 22.7 Amadi et al [39] 346 NA 87. hypertriglyceridemia and low HDL-C. Clinicians need to be aware of this so as to pay a closer attention to the lipid profiles of their patients with T2D.…”