No abstract

No abstract

Purpose: To assess the axial length (AL) measurement failure rate using partial-coherence interferometry (PCI) and swept-source optical coherence tomography (SS-OCT) in dense cataracts. As a secondary outcome, the SS-OCT biometry was compared to immersion ultrasound. Methods: This is a prospective cross-sectional and comparative study. Seventy eyes from 70 patients with dense cataracts were enrolled in this study. Dense cataract was defined according to the Lens Opacities Classification System III (LOCS III) scores equal to or more than NO4, NC4, C4, and P3. The failure rate of AL measurement was evaluated using PCI and SS-OCT. Anterior chamber depth (ACD), lens thickness (LT), and AL measurements obtained by SS-OCT were compared with IUS. Results: AL measurement failure rate with PCI was 68.57% and 21.43% with SS-OCT ( P = 0.007). AL measurement was achieved in 69.23% of NO4, 66.6% of P3, and 15.3% of mixed cataracts using PCI, while SS-OCT was achieved in 100% of NO4, NO5, P3, and P5 and 76.9% of mixed cataracts. Cortical cataracts alone did not influence AL measurement. Biometric data of ACD, LT, and AL were statistically different comparing US and SS-OCT with a good correlation of AL. Conclusion: SS-OCT significantly improves the rate of successful AL measurements when compared to PCI in dense cataracts. The LOCS III clinical cut-off for the use of SS-OCT ocular biometry may well be up to P4 and NO5.

Evaluar la repetibilidad del IOL Master 700, biómetro basado en tomografía de coherencia óptica de fuente de barrido, así como del IOL Master 500, biómetro basado en interferometría de coherencia parcial, además de evaluar su correlación y concordancia, en pacientes candidatos a cirugía de catarata. Diseño del estudio: Comparativo y prospectivo. Métodos: Se obtuvieron los valores de la longitud axial (LA), queratometrías (K), profundidad de cámara anterior (ACD) y distancia blanco-blanco (WTW) con el IOL Master 500, y se compararon con los obtenidos con el IOL Master 700. Se realizó la prueba de t de Student para comparar variables continuas. La correlación de Pearson y el análisis de Bland-Altman se usaron para describir la correlación y el límite de acuerdo entre plataformas. Resultados: El estudio incluyó 55 ojos de 55 pacientes con edad promedio de 69 ± 11 años de edad. La diferencia promedio de LA, K, ACD y WTW fue de 0.16 mm ± 2.30, 0.06 D ± 0.38, 0.02 mm ± 0.12 y 0.15 mm ± 0.67, respectivamente. Existen diferencias estadísticamente significativas entre los biómetros para dos parámetros: LA (p = 0.0003) y ACD (p = 0.038). Conclusiones: La biometría óptica mostró una alta repetibilidad para todos los parámetros en ambos equipos. Los valores de K y WTW mostraron un buen nivel de acuerdo; sin embargo, la LA y la ACD mostraron diferencias estadísticamente significativas entre biómetros ópticos.

Purpose: To assess the repeatability of the swept-source optical coherence tomography (SS-OCT) biometer (IOL Master 700) and evaluate its agreement with a partial coherence interferometry (PCI) biometer (IOL Master 500) in patients undergoing routine cataract surgery. Design: This is a prospective, comparative study. Methods: Axial length (AL), keratometry (k), anterior chamber depth (ACD) and white-to-white distance (WTW) values were obtained by PCI-based biometer and compared with those obtained by SS-OCT. A Student´s t-test was used variables. Pearson's correlation coefficient and Bland-Altman plots were obtained to describe the correlation and limits of agreement between platforms. Results: The study included 55 eyes with a mean age of 69 ± 11 years of age. The mean differences between swept-source and PCI-based biometry for AL, keratometry, ACD and WTW distance were 0.16 mm ± 2.30, 0.06 D ± 0.38, 1.2mm ± 0.12 and 0.15 mm ± 0.67, respectively. There were statistically significant differences between biometers in two parameters: AL (p = 0.0003) and ACD (p = 0.038). Conclusion: SS-OCT biometry showed high repeatability for all biometric parameters. Keratometry and WTW distance values showed a good level of agreement between SS-OCT and PCI-based biometry. However, AL and ACD measurements showed statistically significant differences between the two optical biometers.

No abstract

Objective:The objective of this study was to report the early results of CyberKnife ® (CK ® ) stereotactic radiosurgery in advanced stages of ciliochoroidal (CBCh) melanoma in Mexican patients. Methods: A retrospective review of charts was performed to analyze the outcomes of patients who underwent CK ® (Accuray Inc, Sunnyvale, CA, United States). Results: Four patients with CBCh melanoma were treated under this protocol. The mean age was 53.2 ± 5.3 years (range, 47-60). Median of follow-up was 9.5 ± 3.1 months (range, 5-12). Mean tumor diameter was 13.49 mm, mean thickness, 11.74 mm, and mean gross tumor volume was 1251.97 mm 3 . Tumors were dome-(50%) and mushroom-shaped (50%) in medium-to-large sizes. Three patients had T3b tumors, and one had a T4d tumor at the early tumor staging according to the American Joint Committee on Cancer. A mean dose of 2763 ± 181.3 cGy was prescribed to the 90% isodose line. All patients achieved local tumor control after single-session radiosurgery at the latest follow-up. One patient presented with acute toxicity (extensive serous retinal detachment associated with radiation induced tumor vasculopathy) that was promptly managed. None of the patients required secondary enucleation. Conclusions: CK ® appears to be an effective therapy for medium to large-sized CBCh melanoma. A prospective comparative study with longer follow-up is needed to confirm these findings and to evaluate long-term morbidity.

Objective: To report the early results of CyberKnife ® (CK ® ) stereotactic radiosurgery in advanced stages of ciliochoroidal (CBCh) melanoma in Mexican patients. Method: A retrospective review of charts was performed to analyze the outcomes of patients who underwent CK