The results demonstrate that there was significant reduction in the clinical parameters with improvement in the periodontal status on application of minocycline ointment as an adjunct to periodontal flap surgery in generalized chronic periodontitis.

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Taking care of wounds costs a lot of money. A significant medical problem is the treatment of burns, surgical and trauma wounds and skin wounds, with current therapies primarily emphasizing supportive care techniques. Coagulation, inflammation, angiogenesis, new tissue creation and extracellular matrix modification are necessary processes for successful wound healing. Metal oxides (Titanium, Silver, Zinc, Copper, Magnesium, Nickel) with potent antibacterial and healing characteristics can be employed as nanomaterials in dressings. Metal oxide nanoparticles (MeO-NPs) have a wide range of physicochemical properties that allow them to function as antimicrobial agents through a variety of mechanisms. The treatment of lethal infectious diseases will be impacted by the enormous variety of features demonstrated by MeO-NPs. This study covers the antibacterial mechanisms of common MeO-NPs, factors affecting their antibacterial activity and their role in accelerating wound healing.

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This investigation reports the effect of the addition of CdO nanoparticles on the (Bi,Pb)-2212 superconducting phase. The superconducting samples of general formula (CdO)x Bi1.6 Pb0.4 Sr1.9 Ca1.1Cu2.1 O8 (x = 0.00, 0.01, 0.02, 0.05, and 0.1 wt%) are synthesized using the conventional solid-state reaction technique. Powder X ray diffraction analysis confirms the formation of a single-phase orthorhombic Bi-2212. The variations in the lattice parameters are explained based on the Jahn Teller distortion induced by the increase in the oxygen content owing to the addition of the CdO nanoparticles. The increase in the oxygen content is confirmed via Idiometric titration analysis. The grain morphology is investigated using scanning electron microscopy (SEM). The effect of CdO addition in enhancing grains connectivity by the filing of pores and voids is revealed. Fourier transform infrared (FTIR) spectroscopy is conducted to analyze the functional groups, based on the effect of calcination temperature and CdO addition. Dc-electrical resistivity measurements and I-V characteristics show an enhancement of the superconducting transition temperature (Tc) and the critical current density (Jc) with CdO addition up to x=0.05 wt%, followed by a further decrease. By analyzing the results of the X-ray photoelectron spectroscopy (XPS), the variations of the superconducting properties are explained based on the preferred substitution of Pb2+ ions in the Bi3+ or Cu2+ sites induced by the variations in the oxygen content generated by the addition of CdO nanoparticles.