Hydatid disease caused by Echinococcus granulosus involves liver in 75 % of cases and lung in 15 % of cases. But primary renal involvement without liver and lung involvement is a very rare event. Among these patients of renal hydatidosis, hydatiduria is seen only in 10-20 % cases, which is considered to be pathognomonic. We report a case of echinococcosis, primarily involving the right kidney, presenting with clinical history of hydatiduria.
Abstract:Angiolymphoid hyperplasia with eosinophilia (ALHE) / Epithelioid hemangioma (EH) is a rare lesion commonly located in skin but arising in colon even rarer. It clinically follows a benign course of uncertain pathogenesis characterized histologically by plenty of proliferation of histiocytoid endothelial cells of blood vessels and infiltration by dense eosinophil, lymphocytes and plasma cells. The lesion may recur after excision but there is no report of metastasis. A case of sixty-four years male with severe pain in right iliac fossa with bloody stool had CT scan and noticed ulceration with bleeding sites on colonoscopy. Histopathological examination showed characteristic features of ALHE /EH in common location like skin. The lesion very often mimic as bleeding colonic carcinoma which necessitate colectomy. This is a rare case of ALHE /EH in proximal ascending colon.
: Thalassemia is the world’s commonest monogenic disorder. Molecular biology and genetics have revealed more than 200 mutations of thalassemia syndrome. These children become symptomatic from progressive haemolytic anaemia. They have to take lifelong treatments with regular packed red blood cell transfusion. Our body has no effective means of iron excretion and this leads to progressive iron accumulation in various organs after prolonged blood transfusion. This results in dysfunction of liver, heart and endocrine system and increased mortality. Iron toxicity to pancreatic beta cell leads to impairment in glucose metabolism. : Our study aims to find out the incidence of impaired glucose tolerance (IGT) and diabetes mellitus (DM) in transfusion dependent thalassemia major patients. This is an observational descriptive study carried out from January 2017 to June 2018. The study included 48 samples. There post-prandial blood sugar level and glycated haemoglobin (HbA1c) was analysed. Any proved case of juvenile diabetes mellitus was excluded from the study. We found that the incidence of IGT and DM were 12.5% and 4.16% respectively in our study population. The blood sugar level was significantly high in study group (p=<0.0001) as compared to the control group. The present study showed strong correlation between units of blood transfusion and blood sugar level as well as HbA1C percentage (in both cases p= <0.00001.)Thalassemia patients receiving regular blood transfusion are at increased risk of developing IGT and DM. Early initiation of chelation and judicious use of blood transfusion must be considered for these patients to prevent such complications.
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