Ovarian cancer (OC) is the seventh most common cancer for females in the world. Epithelial OC is the most predominant pathologic subtype (85%-90%), with five major histotypes- serous, mucinous, endometrioid, brenner and clear cell tumour. Each have three pathological subtypes ie benign, borderline and malignant. Mucinous cystadenomas and carcinomas of the ovary are well-established and common tumors. Primary retroperitoneal mucinous cystadenomas and carcinomas are being very rare and histopathogenesis of which is still uncertain. Most pathologists suggest their origin through mucinous metaplasia in a pre-existing mesothelium-lined cyst. An accurate preoperative diagnosis of these tumors is challenging due to lack of established effective diagnostic measures. Hereby presenting a 50-year-old woman, who visited to the hospital with abdominal distension and discomfort since two months. Sonography and computed tomography scans were performed and showed large predominantly cystic lesion arising from right adnexa. Patient underwent exploratory laparotomy for removal of the tumor. Histology and immunohistochemistry revealed primary retroperitoneal mucinous cystadenocarcinoma.
Endometrial Stromal Sarcomas (ESS) are rare tumours arising from the endometrial stroma. The present retrospective study was conducted jointly at the Malabar Cancer Centre, Thalassery and Kannur Medical College, Kannur, Kerala, between June 2011 and June 2015. AIMTo study the age distribution, Histo-morphological features of ESS and to evaluate the prognostic factors of ESS. MATERIALS AND METHODSAll the cases diagnosed as ESS during study period were included and other endometrial malignancies were excluded. Of the 11 cases of ESS, 10 cases were detected at Malabar Cancer Centre, Thalassery, and 1 case at Kannur Medical College, Kannur. OBSERVATIONSThe frequency distribution of the tumour with relation to age is also evaluated. In addition to the classical morphological features, IHC for CD10 is of high value in diagnosis. ER and PR positivity may provide an avenue for hormonal therapy. RESULTSSignificant association was observed between FIGO staging and survival of subjects. As these tumours have tendency for late recurrence, long-term follow-up is essential; i.e. once in 3 months for first year, half yearly for next 4 years and annually thereafter. CONCLUSIONSESS is a rare entity and in addition to the classical morphological features, immune-staining for CD10 is of high value in its diagnosis. ER and PR positivity shows these tumours are amenable to hormonal therapy.
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