ResumenDescribimos un caso de arteriolopatía calcificante urémica asociada, inicialmente, a lesiones cutáneas,en un paciente con insuficiencia renal crónica, en terapia de diálisis peritoneal automatizada, como hallazgos más relevantes presentaba hiperfosfatemia, normocalcemia e hiperparatiroidismo severo sin hiperplasia nodular. Se destaca la mejoría clínica con manejo multimodal de intensificación en la terapia dialítica y tiosulfato de sodio intravenoso.La calcifilaxis es un trastorno que debuta con alta morbilidad y mortalidad, secundaria a sepsis, ocurre con mayor frecuencia en pacientes con insuficiencia renal crónica que se encuentran en hemodiálisis. Se caracteriza por calcificación sistémica en la media de las arteriolas, desencadenándose isquemia y necrosis subcutá-nea de piel y tejidos blandos. La evaluación histopatológica ayuda a confirmar el diagnóstico.Palabras clave: calcifilaxis, tiosulfato de sodio, enfermedad renal crónica, hiperparatiroidismo.Calcific Uremic Arteriolopathy, report of a case treated with Sodium Thiosulfate SummaryWe describe a case of calcific uremic arteriolopathy initially associated with skin lesions within the context of a patient with chronic kidney disease in automated peritoneal dialysis therapy, as most relevant findings presented hyperphosphatemia, normal calcium and severe hyperparathyroidism without nodular hyperplasia. Clinical improvement with multimodal management with intensification of dialysis therapy and Sodium thiosulfate is highlighted. Calciphylaxis is a disorder that presents with high morbidity and mortality secondary to sepsis, occurs most often in patients with chronic kidney disease, who are on hemodialysis. Calciphylaxis is characterized by systemic medial calcification of arterioles and ischemia triggers skin necrosis subcutaneous soft tissue. Histopathologic evaluation helps confirm the diagnosis.
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