Golimumab is a fully human anti-tumour necrosis factor (TNF)-α monoclonal antibody approved for use in the treatment of active rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Psoriasis induced by treatment with anti-TNF drugs is well documented, but to our knowledge, the development of clinical features of psoriasiform exfoliative erythroderma during treatment with golimumab has not been previously described.
Hair-thread tourniquet syndrome (HTTS) is a rare disorder characterized by the encircling of an appendage by a hair or thread. We report an 8-month-old boy with toe HTTS. Early recognition is required to avoid the serious consequences of its delayed diagnosis.
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