Every year, millions of people in the world get bone diseases and need orthopedic surgery as one of the most important treatments. Owing to their superior properties, such as acceptable biocompatibility and providing great primary bone fixation with the implant, polymethyl methacrylate (PMMA)-based bone cements (BCs) are among the essential materials as fixation implants in different orthopedic and trauma surgeries. On the other hand, these BCs have some disadvantages, including Lack of bone formation and bioactivity, and low mechanical properties, which can lead to bone cement (BC) failure. Hence, plenty of studies have been concentrating on eliminating BC failures by using different kinds of ceramics and polymers for reinforcement and also by producing composite materials. This review article aims to evaluate mechanical properties, self-setting characteristics, biocompatibility, and bioactivity of the PMMA-based BCs composites containing carbon nanotubes (CNTs), graphene oxide (GO), and carbon-based compounds. In the present study, we compared the effects of CNTs and GO as reinforcement agents in the PMMA-based BCs. Upcoming study on the PMMA-based BCs should concentrate on trialing combinations of these carbon-based reinforcing agents as this might improve beneficial characteristics.
The need for operative treatment also comes from injury, degeneration, and illnesses. This typically includes removing skeletal components such as ankles, legs, finger joints, wrists, vertebrae, jaws, and other essential organ systems such as the liver, heart, skin, etc. 1 These materials are indicative as a distinctive group of biomedical well-designed materials that most likely conducted a wide range of biological functions in the absence of the specific living tissue/organ, as a consequence, replace the issues found with the defective tissue/ organ and assist the living organism. 1,2 These structural and
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