Introduction: Type 2 diabetes (T2D) is one of the leading causes of death among Asian Americans. Despite being a culturally diverse racial group with differences in history, language, religion, and values, Asian Americans are often viewed as a monolith. With the high prevalence rate of T2D, a careful examination of self-management interventions across Asian Americans is needed to develop effective and culturally sensitive interventions. Objective: To describe existing literature by examining study characteristics, different intervention components, and outcome measures of various T2D interventions among Asian Americans. Methods: Using Arksey and O'Malley's framework to ground this review, six online databases were used to identify studies. Results: A total of 18 publications were included. Thirteen studies were published after 2013, with 44% and 22% of these studies focused on Chinese Americans and Korean Americans. We found a lack of geographic diversity in the location of the studies. Majority of the participants were females. Most of the interventions were implemented in person. Licensed health care providers were the most common interventionists, with a number of studies using community health workers. Outcome measures focused on three key areas: physiological, psychosocial and behavioral, and program-related outcomes. Many of the studies measured changes in HbA1C, self-efficacy, distress, depression, and quality of life. Overall, we saw improvements in physiological measures in most of the studies. For example, majority of the studies showed a decline in the participants' HbA1C. Most studies showed an increase or improvement in healthy behaviors. Studies that measured efficacy, knowledge, attitude, motivation, quality of life, or general health showed improvement from baseline. All the studies that measured distress or depression showed a reduction of symptoms postintervention. Conclusion: Overall, we found that culturally tailored interventions that focus on specific Asian American subpopulations saw an improvement in physiological, psychosocial, or behavioral measures. There were several gaps in the existing T2D self-management programs or interventions among Asian Americans studied in the United States. Based on our analysis, we recommend when designing or implementing self-management interventions among Asian Americans, considerations should be made for targeted recruitment for understudied Asian American subgroups, gender, and location.
Bioremediation of soil contaminated with organic chemicals is a challenging problem in the environmental scenario. On the basis of identification of remediation capability of Helianthus annus (sunflower) assisted with Pseudomonas aeruginosa and Micrococcus luteus were used to investigate the soil contaminated with petroleum hydrocarbons (crude oil) at varying concentrations (25,50,75,100,125, &150ml/ kg of soil) in a pot experiment carried out in a green house. According to both qualitative and quantitative analysis of parameters including plant height, stem girth, number of leaves, leaf area and photosynthetic pigments including chlorophyll a, b and carotenoid indicated that H.annus showed peculiar tolerance to the higher concentration of crude oil concentration in the soil containing both micrococcus and pseudomonas (MP) (combined) consortium showing positive synergetic effect on H.annus in remediating the petroleum hydrocarbons at all concentrations more significantly at higher concentration of crude oil (150ml/kg) of soil. The results show significant increase in growth of (both Micrococcus and Pseudomonas) MP treated plant as compare to control plants; in control the leaf area 18.716 ± 1.256, stem girth 3.40±0.10 and plant height 90.72±4.062 whereas in MP treated plant leaf area 19.65 ±0.292, stem girth 3.580 ±0.048, height 98.20±3.852 respectively. On the whole Helianthus anuus is commercial oil yielding crop that can be effectively applied to phytoremediation of petroleum hydrocarbons assisted with Micrococcus and Pseudomonas is a significant treatment for remediating the soil contaminated with petroleum hydrocarbon.
Background and Objective: Resveratrol is a poly-hydroxyphenol plant toxin that alleviates oxidative stress by increasing endogenous antioxidant levels and prevents tissue damage. The study aimed to investigate the anti-oxidative role of Resveratrol by histochemical, ultrastructural, and biochemical methods in Cisplatin-induced testicular toxicity in Wistar Albino rats. Material and Methods: Quasi-experimental study was conducted at the Department of Pharmacology, Anatomy and Postgraduate Laboratory of ISRA University Hyderabad from October 2020 to March 2021. Twenty-four male, normal adult Wistar albino rats were recruited and distributed equally into; Group-A (Control), Group-B (Experimental group or Cisplatin group), Group-C (Experimental group or Cisplatin + Resveratrol combination group). Pre and post-experimental body weight, analysis of oxidative markers, semen parameters, and histomorphology were carried out in all three groups. SPSS version 24.0 was used for the analysis of Data. Results: A statistically significant decline in the body weight and testicular weight in group B and C respectively (p<0.05). While reduction in sperm count, motility and viability was observed in Group-B compared with Group-C (p<0.05). Oxidative markers were also significantly depleted in Group-B in comparison to Group-C (p<0.05). Evident changes were observed in the testicular histology of Group-B compared with Group-C (p<0.05). Irregular, regressive, and atrophic seminiferous tubules were seen in Group-B. Most seminiferous tubules having normal morphology were observed in Group-C while the number of atrophic and degenerative seminiferous tubules also decreased significantly. Conclusion: Resveratrol is a potent protective agent with promising results in attenuating cisplatin-induced oxidative stress and eventually testicular toxicity.
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