Background
To compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM).
Methods
Four phakic IOLs were used for this prospective, experimental study: two Visian ICL EVO+ V5 lenses and two iPCL 2.0 lenses. All of them were brand new, were not previously implanted in humans, were monofocal and had a dioptric power of − 12 diopters (D). The anterior surface roughness was assessed using a JPK NanoWizard II® atomic force microscope in contact mode immersed in liquid. Olympus OMCL-RC800PSA commercial silicon nitride cantilever tips were used. Anterior surface roughness measurements were made in 7 areas of 10 × 10 μm at 512 × 512 point resolution. The roughness was measured using the root-mean-square (RMS) value within the given regions.
Results
The mean of all anterior surface roughness measurements was 6.09 ± 1.33 nm (nm) in the Visian ICL EVO+ V5 and 3.49 ± 0.41 nm in the iPCL 2.0 (p = 0.001).
Conclusion
In the current study, we found a statistically significant smoother anterior surface in the iPCL 2.0 phakic intraocular lenses compared with the VISIAN ICL EVO+ V5 lenses when studied with atomic force microscopy.
Introduction:The aim of this study was to evaluate the correlation between several ocular parameters (intraocular pressure [IOP], corneal biomechanical properties) and the visual field (VF) mean deviation (VF MD) in eyes with openangle glaucoma (OAG). Methods: We conducted a cross-sectional, observational study in which we measured the IOP with Goldmann applanation tonometry, the central corneal thickness (CCT), and the corneal parameters obtained from the Ocular Response AnalyzerÒ (ORAÒ) and the CorvisÒ ST non-contact tonometer, in newly diagnosed and treatment-naïve eyes with OAG, to investigate whether there was any correlation between these ocular parameters and the VF MD. Results: A total of 51 eyes were analyzed. A statistically significant correlation was found only between the VF MD and corneal hysteresis (CH) (P = 0.003, r 2 = 0.16) and CCT (P = 0.03, r 2 = 0.08). Conclusions: These results demonstrate that CH and CCT are associated with the amount of VF damage in treatment-naïve OAG eyes.
Introduction: It is well known that the femtosecond laser lamellar cut has some degree of roughness. Nevertheless, as in femtosecond laser assisted LASIK (FS-LASIK), an excimer LASIK ablation is performed, the post-ablation stromal bed should show a marked decrease in roughness. We decided to compare, using atomic force microscopy (AFM), the roughness of the corneal stromal bed, after a Femtosecond lasers device (FS) flap was created with or without an excimer myopic ablation.Methods: Using 6 freshly enucleated porcine eyes, we created in every eye a flap using a femtosecond laser. Additionally in 3 eyes an excimer laser ablation to correct -3 diopters (D) was made. AFM imaging of the remaining corneal stroma was performed. Ten different square areas of 20μm x 20μm at the central area of the stroma of each corneal sample were studied. The roughness parameters used was the root-mean-square (RMS) deviation from a perfectly flap plane.Results: The RMS deviation were 360 ± 120 nm in femtosecond laser only, and 110 ± 20 nm in those cases where excimer is also involved (p<0.0001).Conclusions: Our results show that the roughness of the surface treated with excimer is clearly lower than in the group with no excimer ablation, thus the application of laser excimer after a flap creation by femtosecond laser flap creation may soften the nano-irregularities created by this technique.
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