Mesoporous silica (MPS) nanoparticle was prepared as carriers for drug delivery systems by sol-gel method from sodium silicate as inexpensive precursor of silica and Cocamidopropyl betaine (CABP) as template. The silica particles were characterized by SEM, TEM, AFM, XRD, and N2adsorption-desorption isotherms. The results show that the MPS particle in the nanorange (40-80 nm) with average diameter equal to 62.15 nm has rods particle morphology, specific surface area is 1096.122 m 2 /g, pore volume 0.900 cm 3 /g, with average pore diameter 2.902 nm, which can serve as efficient carriers for drugs. The adsorption kinetic of Ciprofloxacin (CIP) drug was studied and the data were analyzed and found to match well with pseudofirst order kinetic model. The CIP drug-loaded mesoporous silica (CIP-mSiO2) nanoparticles has capacity of about 16.3 mg drug/ mg mSiO 2 were achieved, and capable of releasing 26% and 98.6% of their drug content after 90 min in water and PBS solution(pH,7.4) respectively. In-vitro controlled release studies of CIP in Simulated Body Fluid were carried out under stirring conditions. A study on release kinetics and mechanism using Koresmeyer-Pepps model, first order kinetic, and kopcha model shows that the Korsmeyer-Peppas and Kopcha models, both conform more closely to the release data.

No abstract

:The availability, low toxicity, and high degree of technological development make silicon the most likely material to be used in solar cells, the cost of solar cells depends entirely on cost of high purity silicon production. The present work was conducted to electrodeposite of silicon from K 2 SiF 6 , an inexpensive raw material prepared from fluorosilicic acid (H 2 SiF 6 ) produced in Iraqi Fertilizer plants, and using inexpensive graphite material as cathode electrode. The preparation of potassium fluorosilicate was performed at (60 o C) in a three necks flask provided with a stirrer ,while the electro deposition was performed at 750 o C in a three-electrodes configuration with melt containing in graphite pot. High purity potassium fluorosilicate (99.25%) was obtained at temperature (60 o C), molar ratio-KCl/H 2 SiF 6 (1.4) and agitation (600 rpm). Spongy compact deposits were obtained for silicon with purity not less than (99.97%) at cathode potential (−0.8 V vs. Pt), K 2 SiF 6 concentration (14% mole percent) with grain size (130 µm) and level of impurities (Cu, Fe and Ni) less than (0.02%).

The availability, low toxicity, and high degree of technological development make silicon the most likely material to be used in solar cells, the cost of solar cells depends entirely on cost of high purity silicon production. The present work was conducted to electrodeposite of silicon from K 2 SiF 6 , an inexpensive raw material prepared from fluorosilicic acid (H 2 SiF 6) produced in Iraqi Fertilizer plants, and using inexpensive graphite material as cathode electrode. The preparation of potassium fluorosilicate was performed at (60 o C) in a three necks flask provided with a stirrer ,while the electro deposition was performed at 750 o C in a three-electrodes configuration with melt containing in graphite pot. High purity potassium fluorosilicate (99.25%) was obtained at temperature (60 o C), molar ratio-KCl/H 2 SiF 6 (1.4) and agitation (600 rpm). Spongy compact deposits were obtained for silicon with purity not less than (99.97%) at cathode potential (−0.8 V vs. Pt), K 2 SiF 6 concentration (14% mole percent) with grain size (130 µm) and level of impurities (Cu, Fe and Ni) less than (0.02%).

No abstract