Prior to the recommended age for population-based breast cancer screening by mammography, which ranges from 40−50 years depending on guidelines, the main way to identify higher risk women for earlier breast cancer (BC) screening to improve outcomes and discuss targeted chemoprevention is through specific clinical guidelines which are largely based on family history of breast cancer and known mutations in breast cancer susceptibility genes. The annual percent change (APC) in early-onset BC continues to rise, with the higher early-onset cancer burden and mortality continuing to be seen in non-Hispanic black (NHB) women compared to non-Hispanic white (NHW) women. Coupled with the increasing incidence overall as well as the lower percent of BC family history reported in NHB women compared with that of NHW women means that continued reliance on guidelines to identify women for genetic screening and initiation of early BC screening based largely on family history could lead to even greater BC health inequities. The similarity in the prevalence of mutations in key BC susceptibility genes between NHB and NHW women contrasts sharply to the differences in age-specific incidence rates between NHB and NHW women, supporting that there must be environmental modifiers that are contributing to the increased incidence in NHB women. This reality further argues for identifying NHB women early in adulthood through genetic testing who may benefit from tailored BC risk-reduction programs and early BC screening.
This video illustrates the utilization of a patient-specific 3D kidney model to rehearse complex tumor resection prior to the surgery. The implementation of 3D models available to the surgeon prior to RAPN affords preoperative planning and improves the ability to anticipate intricacies of patient-specific anatomy. Moreover, allowing the resident to demonstrate tumor resection capability on a model may increase trainee autonomy and focus teaching during the case.
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