There are a few potential reasons for vocal overlap polyps in grown-ups. The mechanical harm is the fundamental driver for polyp arrangement. Laryngopharyngeal reflux and human papilloma infection are conceivable co-factors. The point of this examination was to discover the related parts of laryngopharyngeal reflux and human papilloma infection in the advancement of grown-up vocal crease polyps. This cross-sectional observational investigation included 50 grown-up patients gave vocal crease polyps. Patients were preoperatively evaluated for the presence of laryngopharyngeal reflux utilizing the approved nine-thing reflux indication file and eight-thing reflux discovering score. All patients were exposed to extraction of the laryngeal polyp by microlaryngoscopic medical procedure. The extracted tests were sent for human papilloma infection (HPV) identification by PCR. Laryngopharyngeal reflux (LPR) was introduced in 34 patients (68%). Reflux side effect list went from 6 to 25 (mean 13.06 ± 4.95). Reflux discovering score went from 3 to 18 (mean 10.08 ± 4.32). Seventeen patients (34%) had positive HPV-6. Fifteen patients had positive HPV-6 out of 34 patients determined to have LPR (44.11%), contrasted with just two patients had positive HPV-6 among 16 patients without LPR (12.5%) (P = 0.027). There were critical relations between presence of HPV-6 and both reflux side effect record and reflux discovering score; both were essentially higher among patients with positive HPV-6 (P = 0.028) and (P < 0.001) individually. Both laryngopharyngeal reflux and human papilloma infection assume significant related functions in the improvement of vocal crease polyps in grown-ups.
Background: Obstructive sleep apnea (OSA) is a common health problem affecting a large number of people all over the world with great psychological and physiological burdens. The aim of this study is to investigate the effect of implantation of septal cartilage and platelet rich plasma in the soft palate as a new technique in treatment of obstructive sleep apnea and snoring. Patients and Methods: This study included 30 Patients with mild to moderate OSA were divided into two groups (A and B) each was 15. Group A: n=15(Tonsillectomy and palatal implantation with septal cartilage). Group B: n=15(Tonsillectomy and platelet rich plasma (PRP) injection). Results: This study found that both techniques improved day time sleepiness with reduction of apnea-hypopnea index (AHI), also there was marked improvement in radiological parameters in the form of increase of the antro-posterior diameter and retro palatal cross-sectional area but also We found superiority of group A over group B in improvement of these parameters that in Group A: success rate was 86.6% while in Group B: it was 80%. No major postoperative complications were recorded. Conclusion: palatal implantation of septal cartilage and platelet rich plasma, both are effective as a treatment of obstructive sleep apnea due to retro-palatal collapse.
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