Background Left ventricular hypertrophy (LVH) is an independent predictor for cardiovascular events in chronic kidney disease (CKD). Objectives To find relationship between left ventricular hypertrophy and CKD stages during predialysis period and assess risk factors in CKD patients for left ventricular hypertrophy. Methods This cross-sectional study of 125 participant with CKD was conducted at Shar Teaching Hospital of Nephrology department, Sulaimani, Iraq. Left ventricular mass index (LVMI) was measured by using two-dimensional echocardiogram in the left decubitus position. LVH was labeled when the left ventricular mass index was >115 g/m² in men, and >95 g/m² in women on echocardiogram. We analyzed the baseline characteristic in 125 patients with chronic kidney diseaase. All patients underwent laboratory investigations which included serum creatinine, complete blood count, serum calcium, phosphate, intact parathyroid hormone, high density lipoprotein cholesterol HDL-C, low density lipoprotein LDL-C, triglyceride, and total cholesterol with urine albumin to creatinine ratio. Results The mean age was 55.27± 14.51 years(male 60.0%, female 40.0%), and the prevalence of LVH was 68.0%, and it was increased with progressive decline in estimated glomerular filtration rate(eGFR) (P =0.005). independent risk factors for LVH were anemia (P =0.000), systolic and diastolic BP (P =0.000; P =0.001 respectively), intact PTH (P =0.038), body mass index BMI(P =0.045), serum calcium (P =0.003),serum phosphate (P =0.001) and majority of lipid profiles. Conclusion There was a high prevalence of LVH in the CKD patients and it was increased with progressively decline in renal function. There was a significant association between systolic and diastolic BP, intact PTH, hemoglobin level, BMI, and minerals with LVH in CKD patients.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.