Aim :To evaluate the effect of addding hyalourindase to bupivacaine in TAP block for lower abdominal surgeries as postoperative analgesia. Methods : fifty patients aged between 20-60 years who were scheduled for lower abdominal surgeries included in the study and divided into two groups,after approval of ethical committee.This study conducted in Sohag university hospitals from September 2016 to March 2017. Patients were divided into two equal groups and all received spinal anesthesia :-(Group A) 25 patients received 20 ml bupivacaine injected in the plane between internal oplique and transversus abdominis musceles.(Group B) 25 patients received 20 ml bupivacaine added to 750 unit hyalourindase. Patients were monitored for heart rate NIBP and oxygen saturation .In post -anesthesia care unit patients were asked to assess their level of pain based on visual analog scale (VAS) , complications also were observed . Results :Our study showes that addition of hyalourindase to bupivacaine for TAP block resulted in significant reduction in VAS pain score over the post operative 24hrs and reduction of post operative morphine requirments .PDF created with pdfFactory Pro trial version www.pdffactory.com SOHAG MEDICAL JOURNAL Postoperative analgesic efficacy of bupivacaine with hyalourindase Vol. 21 No.3 october 2017 Ghada Mohamed Refat
Introduction:Sedation for pediatric cardiac catheterization is a common requirement in many institutions. The goals of the anesthetic management during cardiac catheterization are adequate analgesia, sedation, immobility, and cardiovascular stability (Cravero et al, 2006). Ketamine has potential advantages includeexcellent sedation and analgesia and maintenance of airwayreflexes and respiratory drive. Also, it preserves cardiac function (Williams et al, 2007). Propofol has a predictable onset of action, a short half-life with a rapid recovery time, and is easily titratable. However, propofol is associated with profound respiratory depression, and no analgesic effect (Ewen et al, 1995). Dexmedetomidine is a highly selevtive α2 adrenoceptor agonist with more specificity for the receptor compared to clonidine, approved by FDA in 1999. It provides excellent sedation and analgesia with minimal respiratory depression (Bhana et al, 2000). Aim of work:This study aimed to compare between dexmedetomidine-ketamine and propofol-ketamine combinations in pediatric patients undergoing cardiac catheterization. Patients and methods:After local ethical committee approval an obtained consent from the parents, 44 acyanotic pediatric patients, aged 4 months to 16 years with ASA II and III, analyzed with the chisquare test.
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