Postoperative analgesic efficacy of bupivacaine with hyalourindase in TAP block for lower abdominal surgeries

Abstract

Aim :To evaluate the effect of addding hyalourindase to bupivacaine in TAP block for lower abdominal surgeries as postoperative analgesia. Methods : fifty patients aged between 20-60 years who were scheduled for lower abdominal surgeries included in the study and divided into two groups,after approval of ethical committee.This study conducted in Sohag university hospitals from September 2016 to March 2017. Patients were divided into two equal groups and all received spinal anesthesia :-(Group A) 25 patients received 20 ml bupivacaine injected in the plane between internal oplique and transversus abdominis musceles.(Group B) 25 patients received 20 ml bupivacaine added to 750 unit hyalourindase. Patients were monitored for heart rate NIBP and oxygen saturation .In post -anesthesia care unit patients were asked to assess their level of pain based on visual analog scale (VAS) , complications also were observed . Results :Our study showes that addition of hyalourindase to bupivacaine for TAP block resulted in significant reduction in VAS pain score over the post operative 24hrs and reduction of post operative morphine requirments .PDF created with pdfFactory Pro trial version www.pdffactory.com SOHAG MEDICAL JOURNAL Postoperative analgesic efficacy of bupivacaine with hyalourindase Vol. 21 No.3 october 2017 Ghada Mohamed Refat

Comparison between Morphine and Hyaluronidase Added to Local Anesthetic in Sonar Guided Supraclavicular Brachial Plexus Block; Randomized Double Blinded Controlled Study

“…Our study was supported by Salah et al [22] in 2017 who concluded that addition of hyalourindase to bupivacaine for transversus abdominis plane (TAP) block resulted in significant reduction in VAS pain score over the post-operative 24hours and reduction of postoperative morphine requirements.…”